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A dose-limiting toxicity is: a the total amount of a specific drug that is safely given...

A dose-limiting toxicity is:

a the total amount of a specific drug that is safely given over a patient's lifetime.

b the total dose of a drug given throughout a cycle of treatment.

c a severe side effect that a patient cannot tolerate without life threatening risks.

d a known and expected side effect that is unwanted and unpleasant.

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Answer #1

Option A is correct as

A dose-limiting toxicity is dose dependemt and it is a the total amount of a specific drug that is safely given over a patient's lifetime, at this dose level the drug can be given safely untill the dose is not increased.

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