Question

A maintenance dose of amantadine is 200 mg/day, given in two administrations. If amantadine is given to a patient as a syrup, which has a concentration of 10 mg/ml, for how many days will a 480-ml bottle of drug last?

Answer 1

ANSWER.

* Calculation of how many days will a 480 ml bottle of drug last.

        Volume(ml) of drug required per day

                Volume(ml) = Desired dose/Dose in hand * Quantity.

           Here

                Desired dose(D) = 200 mg/day.

                Dose in hand (H) = 10 mg.

                       Quantity(Q) = 1 ml.

      As per above formula

               Volume(ml) = 200/10 * 1

                                   = 20 ml / day.

         Total volume(ml) of drug in the bottle = 480 ml

       So

            Number of days will the bottle last = 480/20

                                                                     = 24 days.