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there are agents in the environment that, upon exposure, are known to increase an individuals risk of developing cancer. wha
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Cancer is caused by changes to certain genes that alter the way our cells function

Environmental factors causing cancer are:

  1. Tobacco smoking: Tobacco smoke contains over fifty known carcinogens, including nitrosamines and polycyclic aromatic hydrocarbons.
  2. radiation, such as ultraviolet rays from the sun: Ultraviolet (UV) radiation comes from the sun, sunlamps, and tanning booths. It causes early aging of the skin that can lead to skin cancer.
  3. Alcohol consumption: When liver processes alcohol, it will produce acetaldehyde which is carcinogenic. Higher exposure to acetaldehyde will induce a defect in alcohol dehydrogenase gene and tumor suppressor gene (BRCA) inactivation that can lead to the upper gastrointestinal tract, breast and liver cancers.
  4. exposure to asbestos, benzene, benzidine, cadmium, nickel, arsenic, radon and vinyl chloride in the workplace can cause cancer as they alter the genetic composition of a cell. Several accumulated genetic mutations can change a normal cell to malignant one.
  5. Aflatoxins are naturally made mycotoxins which are produced by Aspergillus (fungus). Aflatoxin can intercalate with chromosome DNA base pairs through its epoxide moiety. These changes can cause genetic mutations in the p53 gene. Normally, this gene can prevent cell cycle progression when there are DNA mutations or apoptosis. The codon 249 of the p53 gene seems to be susceptible to aflatoxin causing mutation than other codon.
  6. Air pollution is a significant risk factor for respiratory infections, cardiac disease and lung cancer
  7. Water polluted by several organic compounds such as; oil, plastics, detergents, chloroform, petroleum, polychlorinated biophenyl, fertilizer, sulfur oxide, pesticides and trichloroethylene which cause various human diseases including cancer
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