Question

Medication affecting Reproductive tract: Use of contraceptive transdermal patch

Answer 1

Medications affecting reproductive tract are :-

ESTROGEN

• Conjugated equine estrogens (Premarin)

• Estradiol (Estrace)

• Estradiol hemihydrate (Vagifem)

PROGESTERONE

• Medroxyprogesterone acetate (Provera)

• Norethindrone (Micronor)

• Megestrol acetate (Megace)

HORMONAL CONTRACEPTIVES

• Combination oral contraceptive: ethinyl estradiol and norethindrone (Ovcon 35, Necon 1/35)

• Transdermal patch: ethinyl estradiol and norelgestromin (Ortho Evra)

• Vaginal contraceptive ring: ethinyl estradiol and etonogestrel (Nuva Ring)

• Parenteral: depot medroxyprogesterone acetate DMPA (Depo-Provera, Depo-subQ)

TESTOSTERONE/ANDROGENS

• Testosterone (Andronaq-50, Testred)

• Testolactone (Teslac)

• Testosterone pellets (Testopel)

5-ALPHA REDUCTASE INHIBITORS

• Finasteride (Proscar)

• Dutasteride (Avodart)

ALPHA1-ADRENERGIC ANTAGONISTS

• Tamsulosin (Flomax)

• Silodosin (Rapaflo)

• Alfuzosin (Uroxatral)

• Terazosin (Hytrin)

• Doxazosin (Cardura)

PHOSPHODIESTERASE TYPE 5 (PDE5) INHIBITORS

• Sildenafil (Viagra)

• Tadalafil (Cialis)

• Vardenafil (Levitra)

#. Side effects of using contraceptive transdermal patch :-

- APPLICATION SITE REACTION

- N/V (Estrogen EXCESS)

- BREAST TENDERNESS (Estrogen EXCESS)

- WEIGHT GAIN (Estrogen/Progestin EXCESS)

- ACNE, OILY SKIN (Progestin EXCESS)

- DEPRESSION, FATIGUE (Progestin EXCESS)

- BREAKTHROUGH BLEEDING/SPOTTING

: Early Cycle (Days 1-9) - Estrogen Deficiency

: Late Cycle (Days 10-21) - Progestin Deficiency

#. Other medications that affect reproductive tract are :-