Antigen binding sites of antibody
* Antibodies are Y shaped proteins which is produced by immune system to reduce or
kill the pathogens through antigen -antibody reaction.
* In each tip of the Y shaped structure of antibody contain a paratope or antigen
binding site which bind to antigens present in the body.
* Paratope is the Fab(fragment antigen binding) region of antibody which contain parts of
light and heavy chains of antibody.
The domain of an antibody molecule that is responsible for binding to the antigen is: a. Fab b. Fc c. the carbohydrate region d. antibody light chain e. Ig domain
The binding of an antigen to an antibody can result from all of the following except complement activation opsonization agglutination or precipitation activate T cells. neutralization of the antigen
What are the five results of humoral antigen-antibody binding? List and define each.
B cells can attempt to increase the strength of antibody binding to antigen. In the answer box below, answer the following questions (in order). Where does this occur? What cells provide additional sources of antigen? What is this process called? Does this involve DNA rearrangement/recombination? What enzyme is required for this process(full name)?
Write T/F -specificty of an antibody binding is true to ONE antigen only -papain cleave of igG results in TWO fragments -discovery of J gene supports somatic recombination -affinity labeling reveals hypervaribale regions in light chains ONLY
1 pts T cytotoxic cell activation involves: O antigen binding to antibody on B cells O T cell receptor (TCR) binding to antigen displayed in MHC-II O T cell receptor (TCR) binding to antigen displayed in MHC- natural killer cells 1 pts Question 13 Question 11 1 pts Which of the following is found on the surface of T cells! O All of these O MHC-II O CD and TCR TCR O CD 1 pts Question 12 Question 10 1...
label the image to test your understanding of antibody structure Label the image to test your understanding of antibody structure Fc Hinge regions Complement binding site S-S Fab Disulfide bonds Antigen binding sites Reset
1) Which of the following is true about binding sites in proteins? A. Binding sites often resemble cavities in the surface of the protein. B. Binding sites form on the surface of the protein when a ligand is present. C. Binding sites typically rely on covalent forces for tight binding. D. Amino acids making up the binding site must be located close together in the primary sequence.
1. Opsonization involves: Select one: a. The binding of an antibody to an epitope on a pathogen b. Rearrangement V and J regions of the light chain locus c. Recombination of different V, D, and J regions of the heavy chain locus d. Expression of MHC Class I proteins on all nucleated cells for recognition of self e. Subtle mutation of the heavy and light chain genes to optimize antibody structure 2. Which of these produces and secretes antibodies in...
Is more binding energy released when an enzyme encounters its substrate or when an antibody encounters it eliciting antigen? What is the implication here?