Question

The domain of an antibody molecule that is responsible for binding to the antigen is: a....

The domain of an antibody molecule that is responsible for binding to the antigen is:

a. Fab

b. Fc

c. the carbohydrate region

d. antibody light chain

e. Ig domain

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Answer #1

Answer

a)Fab(fragment antigen binding) domain is responsible for binding to the antigen.there are 2 Fab of Y shape antibody formed after cleavage by protease.

  • Fc is the constant fragment at stem of antibody, not responsible for antigen binding.
  • no carbohydrate are present in antibody.
  • antibody light chain alone cant bind with antigen,it requires heavy variable chain in the form of Fab.
  • Ig domain (immunoglobuline like domain) having role in cell to cell recognition ,not in antigen binding.
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