Write T/F -specificty of an antibody binding is true to ONE antigen only -papain cleave of...
Write T/F
-specificty of an antibody binding is true to ONE antigen only
-papain cleave of igG results in TWO fragments
-discovery of J gene supports somatic recombination
-affinity labeling reveals hypervaribale regions in light chains ONLY
Homework Answers
- True
- FALSE, the given cleavage results in 3 fragments
- true
- FALSE, hypervariable regions which form the antigen-binding site are present in both light and heavy chains
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Write T/F
-specificty of an antibody binding is true to ONE antigen
only
-papain cleave of...
1. Opsonization involves: Select one: a. The binding of an antibody to an epitope on a...
1. Opsonization involves: Select one: a. The binding of an antibody to an epitope on a pathogen b. Rearrangement V and J regions of the light chain locus c. Recombination of different V, D, and J regions of the heavy chain locus d. Expression of MHC Class I proteins on all nucleated cells for recognition of self e. Subtle mutation of the heavy and light chain genes to optimize antibody structure 2. Which of these produces and secretes antibodies in...
Adaptive Immunity questions 1. In which scanario is the Fragment Crystallizable (Fc) potion not needed? a....
Adaptive Immunity questions 1. In which scanario is the Fragment Crystallizable (Fc) potion not needed? a. Oposonization b. Adaptive Dependent Cell cytotoxicity c. Neutralization d. Antibody activation of C1q 2. Which antibody istotope binds with the highest avidity? a. IgM b. IgE c. IgA d. IgG e. IgD 3. Which part of the antibody enables binding to repeated epitopes of variable distance? a. constant region b. light chain c. heavy chain d. hinge e. none of the above 4. Antibodies:...
Which of the following statements is (are) true of a T cell that expresses two α chains (and thus...
Which of the following statements is (are) true of a T cell that expresses two α chains (and thus two different T-cell receptors) as a result of ineffective allelic exclusion of the α chain during rearrangement? There will be two unique TCRs on the surface of this T cell. Engaging either of the T-cell receptors on MHC molecules of the thymic epithelium will result in positive selection. If either T-cell receptor binds strongly to self-peptide presented by self-MHC molecules, the...
please answer all 4 questions Question 11 3 pts A B-cell may be activated by: O...
please answer all 4 questions
Question 11 3 pts A B-cell may be activated by: O A TEH cell O Another B-cell O A cytotoxic T-cell O A natural killer T-cell Question 12 3 pts What happens to centrocytes that have high-affinity (tightly-binding) antigen receptors after somatic hypermutation? They receive survival signals from TFH cells o They cannot process antigen or present it to TFH cells o They undergo phagocytosis by dendritic cells in the "light zone" o They die...
ANSWER ALL QUESTIONS FULLY AND CORRECTLY 5-1 T cells recognize antigen when the antigen a. forms...
ANSWER ALL QUESTIONS FULLY AND CORRECTLY
5-1 T cells recognize antigen when the antigen a. forms a complex with membrane-bound MHC molecules on another host-derived cell b. is internalized by T cells via phagocytosis and subsequently binds to T-cell receptors in the endoplasmic reticulum c. is presented on the surface of a B cell on membrane-bound immunoglobulins d. forms a complex with membrane-bound MHC molecules on the T cell e. bears epitopes derived from proteins, carbohydrates, and lipids. 5-2 a....
2s Antigen-Antibody interactons ooour in which of the foliowing ways? A Opsonization BNecation A D. Complement...
2s Antigen-Antibody interactons ooour in which of the foliowing ways? A Opsonization BNecation A D. Complement Fixation EAl the above are cormect 26 Antigen binding sites of an anibody are locaed in the A. Light chains alone D. Fab regions of the antbody B Heavy chains sioneCF ion of the antbody E. Soft chains alone 27 Nonspecific chemical defenses include D stomach hydrochlorie acid A. lysozyme E. All of the choices are corredt Blacic acid and electrolytes of sweat Cskins...
Case Study: As a member of a research team studying a tribe found in a remote...
Case Study: As a member of a research team studying a tribe found in a remote region of New Guinea, you make the astonishing discovery that they have only two V genes for the L chain and three V genes for the H chain of immunoglobulins. Nevertheless, they seem healthy and able to resist the diversity of pathogenic organisms endemic to the area. Suggest how this might be accomplished 1. The DNA for an H chain in a B cell...
1) T/F In order to amplify a gene by PCR, one needs to know the exact...
1) T/F In order to amplify a gene by PCR, one needs to know the exact DNA sequence of the regions flanking the gene. 2) T/F The initiation complex for translation includes transfer RNA-MET. 3) T/F A mutation that changes the amino acid sequence in a protein sometimes increases the fitness of the individual. 4) T/F A mutation in the TATA box will change the level of gene expression. 5) T/F Pyrimidine dimer formation is a common cause of DNA...
This pathway to complement activation can be initiated by several different signals including the properdin/factor P...
This pathway to complement activation can be initiated by several different signals including the properdin/factor P activation pathway The classical pathway The alternative pathway Lectin pathway All of the above The mechanism that permits Ig to be synthesized in either a membrane-bound or secreted form is: Allelic exclusion Codominant expression The one-turn/two-turn joining rule Differential RNA processing Which of the following allows for recombination in the V(D)J coding regions? IL-2b TdT RAG-½ All of the above Generation of combinatorial diversity...
1) Choose true (T) or false (F) to the following statements: a) Light is a...
1) Choose true (T) or false (F) to the following statements: a) Light is a shower of protons b) Light is a type of energy embodied in electric and magnetic fields c) The speed of light in vacuum is 3.00 x 108 m/s d) The speed of light in vacuum is 3.00 x 108 km/s 2) Choose the correct statement a) We can characterize a wave only by its amplitude b) Electric and magnetic...
please answer all 4 questions
Question 11 3 pts A B-cell may be activated by: O A TEH cell O Another B-cell O A cytotoxic T-cell O A natural killer T-cell Question 12 3 pts What happens to centrocytes that have high-affinity (tightly-binding) antigen receptors after somatic hypermutation? They receive survival signals from TFH cells o They cannot process antigen or present it to TFH cells o They undergo phagocytosis by dendritic cells in the "light zone" o They die...
ANSWER ALL QUESTIONS FULLY AND CORRECTLY
5-1 T cells recognize antigen when the antigen a. forms a complex with membrane-bound MHC molecules on another host-derived cell b. is internalized by T cells via phagocytosis and subsequently binds to T-cell receptors in the endoplasmic reticulum c. is presented on the surface of a B cell on membrane-bound immunoglobulins d. forms a complex with membrane-bound MHC molecules on the T cell e. bears epitopes derived from proteins, carbohydrates, and lipids. 5-2 a....
2s Antigen-Antibody interactons ooour in which of the foliowing ways? A Opsonization BNecation A D. Complement Fixation EAl the above are cormect 26 Antigen binding sites of an anibody are locaed in the A. Light chains alone D. Fab regions of the antbody B Heavy chains sioneCF ion of the antbody E. Soft chains alone 27 Nonspecific chemical defenses include D stomach hydrochlorie acid A. lysozyme E. All of the choices are corredt Blacic acid and electrolytes of sweat Cskins...
Case Study: As a member of a research team studying a tribe found in a remote region of New Guinea, you make the astonishing discovery that they have only two V genes for the L chain and three V genes for the H chain of immunoglobulins. Nevertheless, they seem healthy and able to resist the diversity of pathogenic organisms endemic to the area. Suggest how this might be accomplished 1. The DNA for an H chain in a B cell...
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