0.4 g = 400 mg
So 400 mg of amikacin has to be administered.
250 mg in 1 ml
400 mg in = 1/250 * 400 = 1.6 ml
So 1.6 mk of amikacin should be administered to the IV.
It is to be diluted in 100 ml of D5W and then run over 39 minutes.
So total volume of the solution = 100+1.6 = 101.6 ml
Rate = 101.6/39 = 2.6 ml/min
10 gtt=1 ml
2.6 ml = 2.6 * 10 = 26 gtt
So drops per minute = 26
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