Initial adult dose of Pramipexole = 0.375 mg/day.
Now, according to the question, the daily dose is increased by 0.375 mg every 5 days over 31 days.
Therefore, over a span of 31 days, the dose will be increased 6 times.
As every time the increased dosage is a constant amount of 0.375 mg, after 31 days, total increased dosage
= 6 x 0.375 mg
= 2.25 mg
Therefore, after 31 days, total dosage per day = Initial dosage per day + Increased dosage over time per day
= 0.375 mg + 2.25 mg
= 2.625 mg
Thus, for an adult, after 31 days of increasing dosage, the final daily dose for Pramipexole will be 2.625 mg.
Pramipexole is another drug used in the treatment of Parkinson’s disease that, like levodopa, increases the...
Levodopa, a drug used in the treatment of Parkinson’s disease, has a small initial dose followed by a steady increase over several days. Suppose a patient is given three doses a day. Each administration is 250 mg on the first day, and is increased by 250 mg every fourth day. The maintenance dose is reached after 28 days. Calculate the initial and final daily doses of levodopa administered to the patient.
Levodopa, a drug used in the treatment of Parkinson’s disease, has a small initial dose followed by a steady increase over several days. Suppose a patient is given three doses a day. Each administration is 250 mg on the first day, and is increased by 250 mg every fourth day. The maintenance dose is reached after 28 days. How large is each administration of the maintenance dose?
Levodopa, a drug used in the treatment of parkinsons disease, has a small inital dose followed by a steady increase over several days. suppose a patient is given three doses a day. Each administration is 250 mg on the first day, and is increased by 250 mg every fourth day. The maintenance dose is reached after 28 days. How large is each administration of the maintence dose?
• Discuss the pharmacological treatment of clients with Parkinson’s disease. Describe the therapeutic effect of levodopa, carbidopa, anticholinergics. Discuss the on-off phenomenon and drug holidays.
TR, a 79-year-old man, was diagnosed with Parkinson’s disease 10 years ago. During his early treatment, he took selegiline. The drug dosage was increased to alleviate symptoms. 5. What is the effect of amantadine on symptoms of Parkinson’s disease? 6. What would be an appropriate response to the family’s question concerning the use of amantadine for TR? 7. What are the uses for dopamine agonists and COMT inhibitors? 8. Certain anticholinergic drugs may be used to control Parkinson’s disease symptoms....
Cimetidine is used in the treatment and management of gastric ulcers and gastroesophageal reflux disease. In the case of an active ulcer, cimetidine can be administered continuous by IV infusion at a dose rate of 37.5 mg/hr. If the concentration of the cimetidine solution is 6 mg/ml, then how many milliliters must be available for a 4-hr infusion? Misoprostol is used to prevent NSAID-induced gastric ulcers. A daily dose consists of two tablets administered four times each day. What is...
Levothyroxine sodium is a synthetic form of the hormone thyroxine (T4), which increases the metabolic rate. A typical adult maintenance dose is 1.7 micrograms/day for every kilogram of body mass. For a patient who weighs 194 pounds, how many 25-microgram tablets of levothyroxine sodium must be taken each day? While drugs such as levothyroxine sodium are used to treat hypothyroid conditions, drugs such as methimazole are given to control hyperthyroidism. In severe cases, an adult loading dose can be as...
Another treatment for low calcium levels is ergocalciferol (vitamin D2). An average adult dose is around 2.5 mg/day. If taken in the liquid form, which has a concentration of 0.2 mg/ml, how many milliliters of the drug solution would one daily dose contain?
Drugs A, B, and C are Dopamine Receptor Agonists used to treat Parkinson’s disease. Drug A has an EC50of 30 mg/mL, Drug B has an EC50of 20 µg/mL, and Drug C has an EC50of 40 g/mL. Drug C is 50% less efficacious than Drugs A or B. Graph these drugs on a semi-log graded dose-response curve (all on one graph and label the axis). Can you determine the Kdof each of these drugs from the data (tell me why or why not too: HINT-look...
Estradiol valerate is an estrogen drug used to treat menopausal vasomotor symptoms. A typical dose, administered by deep IM injection, consists of 20 mg once every four weeks. If a vial of estradiol valerate contains 5 ml with a concentration of 10 mg/ml, how many vials will be needed for 40 weeks of therapy? Follitropin alfa is a fertility drug that stimulates follicle maturation and induces ovulation. A typical dose consists of subcutaneous injections of 75 units/day for 14 days....