The biotechnology drug cetuximab (ER-BITUX), used in the treatment of colorectal cancer, has a loading dose...
The biotechnology drug cetuximab (ER-BITUX), used in the treatment of colorectal cancer, has a loading dose of 400 mg/m2administered as an intravenous infusion over a 120-minute period. Using an IV set that delivers 15 drops/mL, calculate
(a) the dose (in mg) for a patient with a BSA of 1.6 m2, and
(b) the rate of delivery, in drops/min, for 250 mL of an IV fluid containing the dose.
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The biotechnology drug cetuximab (ER-BITUX), used in the
treatment of colorectal cancer, has a loading dose...
Cetuximab is an epidermal growth factor receptor (EGFR) inhibitor used for the treatment of metastatic colorectal...
Cetuximab is an epidermal growth factor receptor (EGFR) inhibitor used for the treatment of metastatic colorectal cancer, metastatic non-small cell lung cancer and head and neck cancer. Cetuximab is a chimeric (mouse/human) monoclonal antibody given by intravenous infusion that is distributed under the trade name Erbitux in the U.S. and Canada by the drug company Eli Lilly and Co. The initial dose is 400 mg/m2 administered over 120 minutes and Cetuximab is available in 100 mL vials containing 200 mg...
A drug is ordered with a loading dose of 25 mcg/kg over 10 minutes in 50...
A drug is ordered with a loading dose of 25 mcg/kg over 10 minutes in 50 mL of D5W. This is followed by a continuous infusion of 0.75 mcg/kg/min in 1000 ml of D5W/LR The patient weighs 176 lbs. The drug is available as 1 mg/mL in 5 ml vials. A second IV is prepared for the same patient after the first runs out. It is a continuous infusion at the same rate of 0.75 mcg/kg/min. It contains 10 mg...
In preparing an infusion of the drug trastuzumab, a pharmacist adds 20 ml of bacteriostatic water...
In preparing an infusion of the drug trastuzumab, a pharmacist adds 20 ml of bacteriostatic water for injection to a vial containing 440 mg of the mAb. The resulting solution contains trastuzumab, 21 mg/ml. Using the information: Trastuzumab loading dose: 4 mg/kg with 90 min infusion (a) Calculate the milliliters of solution required for the loading dose for a 165 lb. Patient. (b) The pharmacist then transfers the calculated volume into an infusion bag containing 250 ml of sodium chloride...
In preparing an infusion of the drug trastuzumab, a pharmacist adds 20 ml of bacteriostatic water...
In preparing an infusion of the drug trastuzumab, a pharmacist adds 20 ml of bacteriostatic water for injection to a vial containing 440 mg of the mAb. The resulting solution contains trastuzumab, 21 mg/ml. Using the information: Trastuzumab loading dose: 4 mg/kg with 90 min infusion (a) Calculate the milliliters of solution required for the loading dose for a 165 lb. Patient. (b) The pharmacist then transfers the calculated volume into an infusion bag containing 250 ml of sodium chloride...
In the case of a severe staphylococcal infection, an IV loading dose of the antibiotic oxacillin...
In the case of a severe staphylococcal infection, an IV loading dose of the antibiotic oxacillin consisting of 33.3 mg/min is given for 30 minutes. If the infusion solution consists of 50 ml and there are 15 drops per milliliter of solution, how many drops per minute should be administered? Streptomycin is used to treat tuberculosis and plague. Administered by IM injection, the daily dose of streptomycin is 15 mg for every kilogram of body mass, up to 1000 mg....
An 8-kg infant requires a continuous infusion of drug to run at 1 mL/hour to deliver...
An 8-kg infant requires a continuous infusion of drug to run at 1 mL/hour to deliver 3 mcg/kg per minute. How many milligrams of drug should be added to a 100-ml intravenous infusion solution to achieve the desired infusion rate and dose? Cortisporin Sterile Otic Suspension contains 3.5 mg/mL neomycin, 10 mg/ml hydrocortisone, and 0.1% thimerosal; the directions instruct the patient to instill 3 drops in the affected ear. How many milligrams of hydrocortisone does the patient receive per dose...
Drug T Order: starting dose of 0.7 mcg/kg/min; titrate up by 0.5 mcg/kg/min increments to a...
Drug T Order: starting dose of 0.7 mcg/kg/min; titrate up by 0.5 mcg/kg/min increments to a maximum dose of 5 mcg/kg minute Supply: 50 mg of drug in 250 mL of D5W Patient's weight:219 lbs Starting dose: Starting dose: mcg/min mL/hr Titration dose Titration dose: increase the pump by mcg/min mL/hr Maximum dosemlr Maximum dosemcg/min Drug K is ordered for a patient to start at an infusion rate of 2 mcg/kg/min; increase by 1 mcgkg/min to desired effect up to...
A patient order specifies: "Nitroglycerin 100 mg in 500 mL D5W. Infuse over 6 hours." If...
A patient order specifies: "Nitroglycerin 100 mg in 500 mL D5W. Infuse over 6 hours." If the administration set delivers 60 drops/mL, how many milligrams of drug is this patient receiving per hour? If 500-mL of an intravenous solution contains 0.3 g of a drug, at what flow rate, in milliliters per minute, should the solution be administered to provide 0.5 mg/min of drug? 500-mL of an intravenous solution contain 0.6% of drug in sodium chloride injection. At what flow...
1. An IV bag contains 600mg of a drug in 200mL of NS the flow rate...
1. An IV bag contains 600mg of a drug in 200mL of NS the flow rate in ml/h and the dosage rate in mg/min. 10 B of a drug in 200mL of NS, and must infuse over 2 hours. Find 2. An IVPB bag containing 50 mg of drug in 100mL of solution must intus 2mg/min. If the infusion begins at 0800 h, when will it finish? of solution must infuse at the rate of 3. ANIVPB IS infusing at...
The antifungal drug anidulafungin is administered by IV infusion. The maximum infusion rate is achieved when...
The antifungal drug anidulafungin is administered by IV infusion. The maximum infusion rate is achieved when 260 ml of anidulafungin solution, which has a concentration of 0.77 mg/ml, are delivered in 3 hours. What is the maximum infusion rate in milligrams per minute? A loading dose of voriconazole consists of 5 mg for every kilogram of body mass. This dose is administered as two IV infusions separated by 12 hours. The concentration of the solution is 10 mg/ml. If a...
A drug is ordered with a loading dose of 25 mcg/kg over 10 minutes in 50 mL of D5W. This is followed by a continuous infusion of 0.75 mcg/kg/min in 1000 ml of D5W/LR The patient weighs 176 lbs. The drug is available as 1 mg/mL in 5 ml vials. A second IV is prepared for the same patient after the first runs out. It is a continuous infusion at the same rate of 0.75 mcg/kg/min. It contains 10 mg...
An 8-kg infant requires a continuous infusion of drug to run at 1 mL/hour to deliver 3 mcg/kg per minute. How many milligrams of drug should be added to a 100-ml intravenous infusion solution to achieve the desired infusion rate and dose? Cortisporin Sterile Otic Suspension contains 3.5 mg/mL neomycin, 10 mg/ml hydrocortisone, and 0.1% thimerosal; the directions instruct the patient to instill 3 drops in the affected ear. How many milligrams of hydrocortisone does the patient receive per dose...
Drug T Order: starting dose of 0.7 mcg/kg/min; titrate up by 0.5 mcg/kg/min increments to a maximum dose of 5 mcg/kg minute Supply: 50 mg of drug in 250 mL of D5W Patient's weight:219 lbs Starting dose: Starting dose: mcg/min mL/hr Titration dose Titration dose: increase the pump by mcg/min mL/hr Maximum dosemlr Maximum dosemcg/min Drug K is ordered for a patient to start at an infusion rate of 2 mcg/kg/min; increase by 1 mcgkg/min to desired effect up to...
A patient order specifies: "Nitroglycerin 100 mg in 500 mL D5W. Infuse over 6 hours." If the administration set delivers 60 drops/mL, how many milligrams of drug is this patient receiving per hour? If 500-mL of an intravenous solution contains 0.3 g of a drug, at what flow rate, in milliliters per minute, should the solution be administered to provide 0.5 mg/min of drug? 500-mL of an intravenous solution contain 0.6% of drug in sodium chloride injection. At what flow...
1. An IV bag contains 600mg of a drug in 200mL of NS the flow rate in ml/h and the dosage rate in mg/min. 10 B of a drug in 200mL of NS, and must infuse over 2 hours. Find 2. An IVPB bag containing 50 mg of drug in 100mL of solution must intus 2mg/min. If the infusion begins at 0800 h, when will it finish? of solution must infuse at the rate of 3. ANIVPB IS infusing at...
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