Question

a hospital pharmacist reconstitutes a vial containing 2 g of piperacillin sodium to 10 mL with sterile water for injection. This solution is then diluted by adding 100 mL of 5% dextrose injection for administration by infusion. What is the concentration (in mg/mL) of piperacillin sodium in the infusion solution? Show work

Answer 1

ANSWER.

* Calculation of concentration of piperacillin sodium (mg/ml) in the infusion

   solution.

                     Formula = Mass of the solute(mg) / Mass of the solution(ml).

                             Mass of the solute = 2gm

                       Convert gm value to mg for calculation.

                          So

                               Mass of the solute (mg) = 2000 mg. (1g =1000mg).

                               Mass of the solution(ml) = 100 ml.

          As per formula

             Concentration of piperacillin in the infusion solution = 2000 / 100

                                                                                                 = 20 mg/ml.

                      

Answer 2

2g=2,000mg 10ml+100ml=110ml 2,000mg/110mg=18.18mg/ml

Answer 3

2g=2,000mg 10ml+100ml=110ml 2,000mg/110mg=18.18mg/ml