Question

A. Adrenergic Agonist 1. Give the following information on the medication class above: Drug class, Pharmacokinetics (including absorption, distribution, metabolism, excretion), Pharmacodynamics (including onset of action, peak effect, duration), and Therapeutic effects.

Answer 1

Adrenergic agonist

Adrenergic agonist drugs are the drugs that helps triger the effect from adrenergic receptors in body.

Drug class- sympathomimetic amine

Pharmacokinetics-

Uptake and absorption- the absorption of adrenergic agonist takes place in either of the two forms- uptale 1 where the drug interact at presynaptic level to prevent neurotransmitter and uptake 2 is at postsynaptic level that will provide inhibition at peripheral cells.

Metabolism- it increases activation of adrenergic receptors and increase activities such as lipolysis and increase fatty acid metabolism and enhance gluconeogenesis in liver.

Excretion- these drugs either gets excreted in urine or firther metaboloze into monoamines.

Pharmacodynamics-

it works on mymembrane of cell at onset of about 20 kinutes and peak effect of 3 to 5 hours.

Therapeutic use- used to treat nasal congestion, sinusitis, allergic rhinitis, wheezing, cough, bronchial asthma and shortness of breath.