Question

Can you name two substances that are released when there is injury to the tissue as...

  1. Can you name two substances that are released when there is injury to the tissue as it relates to pain transmission?

  1. Can you discuss the difference between “A” fibers and “C” fibers.
  1. What does each letter mean OLD CART and list one question you would ask for each? Use the chart below.

Letter

Meaning

Question

O

L

D

C

A

R

T

Define each classification of pain

Central

Cancer

Deep

Neuropathic

Phantom

Referred

Somatic

Vascular

Visceral

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Answer #1

Can you name two substances that are released when there is an injury to the tissue as it relates to pain transmission?

  • Substance P and Calcitonin gene-related peptide (CGRP)

Difference between “A” fibers and “C” fibers?

A fibers C fibers
  • They are myelinated
  • They are non-myelinated
  • Diameter is large
  • Diameter is small
  • Has a rapid conduction speed of 70-120m/sec
  • It has a slow conduction speed of 0.2-2 m/sec.
  • Fast pain
  • Slow pain
  • Sharp and pricking type of pain but is localized
  • Dull, burning pain but scattered pain
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