If sickle cells (drepanocytes) were seen on the peripheral smear, what test might be indicated as...
If sickle cells (drepanocytes) were seen on the peripheral smear, what test might be indicated as a followup?
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Hemoglobin |
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Hematocrit |
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Hemoglobin electrophoresis |
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Kleihauer-Betke Quantification Test |
Homework Answers
3. In sickle cell anemia the affected hemoglobin molecules mis-shapens when there is less oxygen which makes erythrocytes sickle shaped. Hemoglobin eletrophoresis is a typical blood test which is ordered for people with sickle cell anemia, This test detects all types of hemoglobin. It is also known as sickle cell screen.
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If sickle cells (drepanocytes) were seen on the peripheral
smear, what test might be indicated as...
A patient has an RDW of 18.2%. What should be seen in the peripheral smear? Macrocytosis...
A patient has an RDW of 18.2%. What should be seen in the peripheral smear? Macrocytosis O Microcytosis Anisocytosis Poikilocytosis
Anemias Case Study A 5 year old son of a Liberian exchange student was hospitalized because...
Anemias Case Study A 5 year old son of a Liberian exchange student was hospitalized because of severe diarrhea, abdominal distention and splenomegaly. On admission the following tests were ordered: CBC, bilirubin, hemoglobin electrophoresis, electrolyte studies, urinalysis and stool culture. The results of these tests were as follows: WBC: 8,700/ul RBC: 2.06 x 106/ul Hb: 5.8 g/dl HCT: 19.6% MCV: 96.4 fl MCHC: 32 g/dl PLT: 420,000/ul The peripheral blood smear revealed moderate aniso, 4 + poik, 3+ poly, occasional...
4) If smears are too thick, what might happen? a) The cells might wash off of...
4) If smears are too thick, what might happen? a) The cells might wash off of the slide during decolorization. b) The shape of individual cells will be distorted. c) The smear might stain incorrectly. d) A and B
The patient is a pregnant female, 7 months gestation, who has a routine screening test for...
The patient is a pregnant female, 7 months gestation, who has a routine screening test for hemoglobin and hematocrit. Both are decreased with an elevated MCV (125fL), elevated RDW and normal MCHC. Her white blood cell count is normal and her platelet count is minimally decreased. Review of the peripheral smear revealed macro-ovalocytes, anisocytosis, teardrop cells, and a rare Howell-Jolly body. What blood tests would you like to see at this point? Her serum iron is normal, serum ferritin is...
Do red blood cells have a nucleus? Depending on your slide, you might have seen some...
Do red blood cells have a nucleus? Depending on your slide, you might have seen some purple circles mixed into with the red blood cells. What other cells are found in blood?
0.5. What fraction of the offsprings of two parents with Sickle cell trait would you expect...
0.5. What fraction of the offsprings of two parents with Sickle cell trait would you expect to have Sickle cell anemia? Q.6. List the major steps you undertake for performing ELISA? 0.7. Describe an ELISA procedure you'll undertake to determine if a person is infected with AIDS virus? Q.3. In the two protein gel electrophoresis labs done in this class, proteins were separated based on their net charge or their size (weight). Explain similarities and differences between these two laboratory...
Case Study Ab20-year-old woman was seen by her physician for fatigue, pallor, and easy bruising. Physical...
Case Study Ab20-year-old woman was seen by her physician for fatigue, pallor, and easy bruising. Physical examination was unremarkable except for pallor, widespread petechiae, ecchymosis, and bleeding gums. The spleen was not enlarged. There was no history of recent exposure to drugs, toxins, or radiation. There was no history of any other illness, and she had been in good health until the past 2 weeks. Laboratory data revealed a normochromic, normocytic anemia with a hematocrit of 20%, WBC of 20...
What do the results in Table 22.4 suggest about sickle-cell hemoglobin and malaria? A hemoglobin genotype...
What do the results in Table 22.4 suggest about sickle-cell hemoglobin and malaria? A hemoglobin genotype in children normal (homozygous normal) mild sickling (heterozygous) B hemoglobin genotype in adult males normal (homozygous normal) mild sickling (heterozygous) percent with malaria parasite present 45.7 27.9 percent with malaria parasite present 93.3 percent with high parasite density 66.0 33.3 percent with high parasite density 40.0 0 13.3 Table 22.4. Incidence of the malaria parasite in blood of normal and sickle-cell children from a...
What do the results in Table 22.4 suggest about sickle-cell hemoglobin and malaria? A hemoglobin genotype...
What do the results in Table 22.4 suggest about sickle-cell hemoglobin and malaria? A hemoglobin genotype in children normal (homozygous normal) mild sickling (heterozygous) B hemoglobin genotype in adult males normal (homozygous normal) mild sickling (heterozygous) percent with malaria parasite present 45.7 27.9 percent with malaria parasite present 93.3 13.3 percent with high parasite density 66.0 33.3 percent with high parasite density 40.0 0 Table 22.4. Incidence of the malaria parasite in blood of normal and sickle-cell children from a...
CASE STUDY I: A 42-year-old woman presented with a 2-month history of fatigue and weakness and...
CASE STUDY I: A 42-year-old woman presented with a 2-month history of fatigue and weakness and a 2-week history of a sore throat. She reported a 15-pound weight loss over the past month or two. One week prior to admission she started antibiotics for her sore throat, but she reported little improvement; she subsequently developed a peritosillar abscess. On admission to the hospital she was found to have an elevated white blood cell count with a large number of circulating...
A patient has an RDW of 18.2%. What should be seen in the peripheral smear? Macrocytosis O Microcytosis Anisocytosis Poikilocytosis
0.5. What fraction of the offsprings of two parents with Sickle cell trait would you expect to have Sickle cell anemia? Q.6. List the major steps you undertake for performing ELISA? 0.7. Describe an ELISA procedure you'll undertake to determine if a person is infected with AIDS virus? Q.3. In the two protein gel electrophoresis labs done in this class, proteins were separated based on their net charge or their size (weight). Explain similarities and differences between these two laboratory...
Case Study Ab20-year-old woman was seen by her physician for fatigue, pallor, and easy bruising. Physical examination was unremarkable except for pallor, widespread petechiae, ecchymosis, and bleeding gums. The spleen was not enlarged. There was no history of recent exposure to drugs, toxins, or radiation. There was no history of any other illness, and she had been in good health until the past 2 weeks. Laboratory data revealed a normochromic, normocytic anemia with a hematocrit of 20%, WBC of 20...
What do the results in Table 22.4 suggest about sickle-cell hemoglobin and malaria? A hemoglobin genotype in children normal (homozygous normal) mild sickling (heterozygous) B hemoglobin genotype in adult males normal (homozygous normal) mild sickling (heterozygous) percent with malaria parasite present 45.7 27.9 percent with malaria parasite present 93.3 percent with high parasite density 66.0 33.3 percent with high parasite density 40.0 0 13.3 Table 22.4. Incidence of the malaria parasite in blood of normal and sickle-cell children from a...
What do the results in Table 22.4 suggest about sickle-cell hemoglobin and malaria? A hemoglobin genotype in children normal (homozygous normal) mild sickling (heterozygous) B hemoglobin genotype in adult males normal (homozygous normal) mild sickling (heterozygous) percent with malaria parasite present 45.7 27.9 percent with malaria parasite present 93.3 13.3 percent with high parasite density 66.0 33.3 percent with high parasite density 40.0 0 Table 22.4. Incidence of the malaria parasite in blood of normal and sickle-cell children from a...
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