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A case-control study of the relationship between asthma and a history of pertussis vaccination among children...

A case-control study of the relationship between asthma and a history of pertussis vaccination among children (2-3 years old) was conducted in one community. Although overall participation was good, not all parents of cases and controls could be interviewed. A difference in the proportion interviewed based on case/control status (asthma/no asthma) and based on day care enrollment was identified by the investigators. Only 63% of control parents with a child enrolled in day care could be interviewed, versus 82% of control parents with a child who was not enrolled in day care. In comparison, 93% of case parents were interviewed, a percentage that was the same for parents of children who were and were not enrolled in day care. In this study, how could “enrollment in day care” confound the association between asthma and pertussis vaccination?

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This could confound the result by giving variation or difference in the actual results when compared with enrolled and nonenrolled parents an children.Bias can occur due to this type of research study I'm the result.The exact relationship between asthma and the vaccination history can be got. Moreover missing certain subjects during the interview can give an error in the research study.

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