how do protease inhibitors work?
Homework Answers
Protease is an enzyme in the body that play important role in the replication of HIV. Protease enzyme catalyzes proteolysis and causes the breakdown of proteins into smaller polypeptides or single amino acids. Protease inhibitors block the action of protease enzymes. This prevents protease enzymes from doing their part in allowing HIV to multiply, interrupting the HIV life cycle as a result. This helps to stop the virus from multiplying.
is it possible for HIV protease inhibitors to affect cellular protease?
is it possible for HIV protease inhibitors to affect cellular protease?
Drugs that are HIV protease inhibitors Multiple Choice prevent HIV protease from degrading host cell proteins...
Drugs that are HIV protease inhibitors Multiple Choice prevent HIV protease from degrading host cell proteins О block the translation of HIV proteases bind to HIV proteases prevent HIV proteases from breaking apart capsid proteins bind to HIV proteases and prevent the proteases from breaking apart capsid proteins
Many patients become resistant to HIV protease inhibitors with the passage of time owing to mutations...
Many patients become resistant to HIV protease inhibitors with the passage of time owing to mutations in the HIV gene that encodes the protease. Provide a detailed rationale for the observation that mutations are not found in the active site aspartate residues.
How do antidepressants, such as MAOIs and selective serotonin reuptake inhibitors work? Why might an MAOI...
How do antidepressants, such as MAOIs and selective serotonin reuptake inhibitors work? Why might an MAOI work for one person and a selective serotonin reuptake inhibitor work for another?
Discuss the following medications: cephalosporins, aminoglycosides, penicillins, tetracyclines, rifampin, INH, acyclovir, Atripla, ritonavir, zidovudine, protease inhibitors,...
Discuss the following medications: cephalosporins, aminoglycosides, penicillins, tetracyclines, rifampin, INH, acyclovir, Atripla, ritonavir, zidovudine, protease inhibitors, NRTI’s, NNRTI’s, Truvada, AZT, nystatin, amphotericin, fluconazole, clotrimazole
How do selective serotonin reuptake inhibitors produce their antidepressant effect?
How do selective serotonin reuptake inhibitors produce their antidepressant effect?
14. HIV-1 Protease is an enzyme made by HIV that hydrolyzes the long viral polyprotein into...
14. HIV-1 Protease is an enzyme made by HIV that hydrolyzes the long viral polyprotein into their functional protein components. HIV patients are treated with inhibitors of HIV Protease, which in turn inhibit HIV replication. Two competitive inhibitors of HIV-1 Protease are saquinavir (K = 0.40 nM) and ritonavir (K1 = 0.015 nM). (K, are dissociation constants for the reaction IE + I + E, where I is the inhibitor and E is HIV Protease.) a) Which would have a...
biochemistry: how do noncompetitive, mixed, and uncompetitive inhibitors affect Km and Vmax?
biochemistry: how do noncompetitive, mixed, and uncompetitive inhibitors affect Km and Vmax?
Describe the Renin-Angiotensin-Aldosterone System. ACE inhibitors are commonly prescribed meds for hypertension. Why do these work...
Describe the Renin-Angiotensin-Aldosterone System. ACE inhibitors are commonly prescribed meds for hypertension. Why do these work to lower BP? In your opinion, does the use of ACE inhibitors address the causative problem of hypertension (meaning: do all hypertensives have overactive Angiotensin Converting Enzymes?)? Be sure to thoroughly explain your position from the standpoint of this unit AND previous unit material.
How do competitive inhibitors affect the KM and Vmax of an enzyme? Draw a plot of...
How do competitive inhibitors affect the KM and Vmax of an enzyme? Draw a plot of velocity as a function of substrate concentration, both with and without inhibitor added.
Drugs that are HIV protease inhibitors Multiple Choice prevent HIV protease from degrading host cell proteins О block the translation of HIV proteases bind to HIV proteases prevent HIV proteases from breaking apart capsid proteins bind to HIV proteases and prevent the proteases from breaking apart capsid proteins
14. HIV-1 Protease is an enzyme made by HIV that hydrolyzes the long viral polyprotein into their functional protein components. HIV patients are treated with inhibitors of HIV Protease, which in turn inhibit HIV replication. Two competitive inhibitors of HIV-1 Protease are saquinavir (K = 0.40 nM) and ritonavir (K1 = 0.015 nM). (K, are dissociation constants for the reaction IE + I + E, where I is the inhibitor and E is HIV Protease.) a) Which would have a...
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