Acyclovir sodium comes as a solution for IV use at a concentration of 50 mg/mL. A...
Acyclovir sodium comes as a solution for IV use at a concentration of 50 mg/mL. A pediatric patient weighing 10 kg and 55 cm tall is to be dosed at a rate of 500 mg/m2 infused over 60 minutes. What volume of the product should be added to a 250 mL bag of D5W and at what rate (mL/minute) should the infusion be run?
(Use the Mostellar equetion for BSA)
Thank you!
Homework Answers
Available acyclovir sodium - 50mg/ml
Weight of the patient - 10kg
Prescribed dose - 500mg/meter square = 150mg
Height of the patient - 55cm
BSA = √weight × height /3600
= √10×55/3600
= 0.3meter square
Time of infusion - 60min
Available acyclovir is 50mg/ml ( 1ml has 50mg )
So, we need 3ml for 150mg
3ml of acyclovir sodium has to be added to a 250ml of bag of D5W
Flow rate = total volume /total time
= 250ml /60min
= 4.1ml/min
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