ANSWER.
* Calculation of rate of infusion.
Rate(ml/hr) = Volume(ml) /Time(hr)
Calculation of volume.
Formula = Desired dose/Dose in hand * Quantity.
Here
Ordered dose = 10 mcg/kg/min.
Weight of the patient = 168 pounds.
Convert pound to kg for calculation
1 pound = 0.454 kg.
Weight of the patient = 168 * 0.454
= 76.3 kg.
So
Desired dose(D) = 10 * 76.3
= 763 mcg.
Convert mcg to mg for calculation
1 mcg = 0.001 mg.
So
Desired dose(D) = 763 * 0.001
= 0.76 mg.
Dose in hand (H) = 250 mg.
Quantity (Q) = 250 ml
As per above formula for calculating volume
Volume of drug required = D/H * Q
= 0.76 / 250 * 250
= 0.76 ml / min.
Convert ml/min to ml/hr by multiply with 60.
Rate (ml/hr) = 0.76 * 60
= 45.6 ml/hr.
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