What is TAP and what is its function? what happens to individuals who have a deficiency...
What is TAP and what is its function? what happens to individuals who have a deficiency in TAP? What is this condition called? What are some of its associated symptoms?
Homework Answers
TAP sands for transporter associated with antigen presentation protein. It belongs to the family of ATP binding cassette transporter which is present in ER lumen.
Function : TAP proteins help in transport of peptides from cytosol to the endoplasmic reticulum where it is loaded and represented on MHC I which helps in T cell recognition.
Deficiency of TAP is known as TAP deficiency syndrome. Deficiency of TAP protein causes immunodeficiency disorders.
Some common symptoms associated with TAP deficiency are recurrent infections of ear, nose, throat, lungs and skin like nasal polyps, sinusitis, otitis media, upper and lower respiratory infection and granulomatous skin lesions
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What is TAP and what is its function? what happens to
individuals who have a deficiency...
Assignment: Using your text and LibGuide - What disorder is associated with iron deficiency--describe the disease in at...
Assignment: Using your text and LibGuide - What disorder is associated with iron deficiency--describe the disease in at least 50 words. What are 4 signs and symptoms of iron deficiency? How is the condition treated? What populations are most at-risk?
Individuals who inherit mutations in p53 would be expected to have what symptoms? See Section 19.6...
Individuals who inherit mutations in p53 would be expected to have what symptoms? See Section 19.6 A tendency to sunburn Higher likelihood of developing various types of cancer Higher ability to tan when exposed to sunlight No symptoms, unless the patient is exposed to abnormally high UV radiation
Individuals who inherit mutations in p53 would be expected to have what symptoms? See Section 19.6...
Individuals who inherit mutations in p53 would be expected to
have what symptoms? See Section 19.6 ( page 393) .
Higher ability to tan when exposed to sunlight
Higher likelihood of developing various types of cancer
A tendency to sunburn
No symptoms, unless the patient is exposed to abnormally high
UV radiation
Why Pythagoras wouldn’t eat Falafel: A story about Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency Fava beans, an ingredient...
Why Pythagoras wouldn’t eat Falafel: A story about Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency Fava beans, an ingredient of falafel, have been an important food source in the Mediterranean and Middle East since antiquity. The Greek philosopher and mathematician Pythagoras prohibited his followers from dining on fava beans, perhaps because they made many people sick with a, sometimes fatal, condition called favism. In favism, erythrocytes begin to lyse 24-48hrs after ingestion of the beans, releasing free haemoglobin into the blood. Jaundice and...
7. Both children have pathogenic bacteria (Hemophilus and pneumococci) in their sputum even though their MHC...
7. Both children have pathogenic bacteria (Hemophilus and pneumococci) in their sputum even though their MHC Class II molecules function normally. Is this directly or indirectly due to their MHC class I deficiency? Explain. 8. How is it possible that the children have high antibody titers to some viruses and low titers to others? 9. What is the role of the TAP proteins?How do the TAP proteins relate to this case study?
Individuals with high self-efficacy believe that they: A have the ability to get things done. (B)...
Individuals with high self-efficacy believe that they: A have the ability to get things done. (B) control what happens to them. C compliment individuals who give them positive feedback. D engage in more organizational citizenship behaviors.
within today's health sector many individuals who have been in the workforce for 20 years greater...
within today's health sector many individuals who have been in the workforce for 20 years greater are experiencing challenges with the usuages of EHR. Based on your experiences what are some potential barriers that consumers might incur.
A business entity formed by two or more individuals who each have unlimited liability for business...
A business entity formed by two or more individuals who each have unlimited liability for business debts is called a A. corporation. B. sole proprietorship. C. general partnership. D. limited partnership. E. limited liability company.
There are three overlapping clinical syndroms associated with deficiencies in HGRT activity. Individuals with at least...
There are three overlapping clinical syndroms associated with deficiencies in HGRT activity. Individuals with at least 8% activity of normal individuals present with overproduction of uric acid and associated gout, a condition called Kelley-Speegmiller syndrome. Patients with 1.5%-8% have neurological disability that ranges from clumsiness to debilitating motor dsyfunction in addition to uric acid overproduction problems. Patients with less than 1.5% HGPRT activity have Lesch-Nyhan syndrom. Provide possible explanations for the differences in HGPRT activity in the different syndromes.
6. A researcher studying a Parkinson-like disease in an isolated population discovered that several individuals who...
6. A researcher studying a Parkinson-like disease in an isolated
population discovered that several individuals who developed
symptoms at an average age of 52.3 years have a D2S44 allele (R)
that is common in this population but not found outside of the
population. A study of members of the population and members of a
similar population that does have the allele (+) was done and the
numbers of individuals with Parkinson-like symptoms were recorded
(Table).
a. Is there an association...
Individuals who inherit mutations in p53 would be expected to have what symptoms? See Section 19.6 A tendency to sunburn Higher likelihood of developing various types of cancer Higher ability to tan when exposed to sunlight No symptoms, unless the patient is exposed to abnormally high UV radiation
Individuals who inherit mutations in p53 would be expected to
have what symptoms? See Section 19.6 ( page 393) .
Higher ability to tan when exposed to sunlight
Higher likelihood of developing various types of cancer
A tendency to sunburn
No symptoms, unless the patient is exposed to abnormally high
UV radiation
Individuals with high self-efficacy believe that they: A have the ability to get things done. (B) control what happens to them. C compliment individuals who give them positive feedback. D engage in more organizational citizenship behaviors.
6. A researcher studying a Parkinson-like disease in an isolated
population discovered that several individuals who developed
symptoms at an average age of 52.3 years have a D2S44 allele (R)
that is common in this population but not found outside of the
population. A study of members of the population and members of a
similar population that does have the allele (+) was done and the
numbers of individuals with Parkinson-like symptoms were recorded
(Table).
a. Is there an association...
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