Question

Individuals who inherit mutations in p53 would be expected to have what symptoms? See Section 19.6 A tendency to sunburn Higher likelihood of developing various types of cancer Higher ability to tan when exposed to sunlight No symptoms, unless the patient is exposed to abnormally high UV radiation

Answer 1

Answer : The correct answer is C ( Higher likelihood of developing various cancers)

Explanation: P53 (tumor suppressor gene) is a nuclear phosphoprotein whose mutation is associated with most of the cancers. As such, p53 has been described as "The guardian of the genome” because of its role in conserving genome stability by preventing genome mutation. Mutations in P53 results in a syndrome called Li–Fraumeni syndrome in which individuals are highly prone to development of various cancers.