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2. Blood is buffered using a bicarbonate system primarily to accommodate the formation of CO2 in...

2. Blood is buffered using a bicarbonate system primarily to accommodate the formation of CO2 in the tissues. The overall pK for the reaction below is 6.35:

CO2 + H2O  H2CO3  H+ + HCO3

During acidosis, treatment can consist of IV administration of NaHC03. If the pH of blood is typically 7.4, and the total concentration of carbonic acid/ bicarb is 0.05M, what is the concentration of conjugate base and acid in blood?

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Answer:-

This question is solved using the Henderson Hesselbalch equation for buffer. Then the concentration is calculated.

The answer is given in the image,

Ansuler;- CO2 +H20→ H2 CO3 Ht +HCO3 pka= 6.35, pu=7.40 To tal contentration = 0.05 M CH2C03] +(HCO5]=0-050M O PH= pka +log TH

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