Amount of usable energy (energy that can do work) in a system is Gibbs free energy. The spontaneity of a reaction can be measured using change in Gibbs free energy.
a. Change in Gibbs free energy or ∆G can be calculated as:
ΔG=∆G forward–∆G reverse
In the reaction ATP + Creatine + water - creatine phosphate + ADP+ pi
∆G reverse= - 43.1kj/ mole
∆G forward= - 30.5 kj/ mole
∆G = -30.5-(-43.1)= 12.6kj/ mole
b. Since ∆G is positive means the reaction is nonspontaneous and endergonic.
2. For the following reaction: ATP+ creatine + H2O creatine phosphate + ADP + P, The...
To answer this question, please reference the Problem Solving Video: Free Energy, ATP, and Creatine in Resting Muscles. The standard free energy, AGⓇ', value for an enzymatic reaction with several al components is the sum of the AGⓇ values for each component. Creatine kinase catalyzes the transfer of a phosphate group from creatine phosphate to ADP to form ATP. Standard Free Energy of Hydrolysis Standard E Compound kJ.mol-1 creatine phosphate -43.1 ATP (to ADP) -30.5 creatine phosphate +H,0 creatine +...
10) The AG for the hydrolysis of creatine phosphate is -43.1 k/mol, whereas the AG for ATP synthesis is+30.5 kj/mol, what is the overall ΔG., for the reaction shown below? creatine + ATP creatine phosphate+ADP O-73.6 kj/mol O12.6 k/mol -43.1 k/mol O73.6 k/mol -12.6 kj/mol 043.1 Wmol Answer not listed
Given the following: phosphocreatine → creatine + Pi ΔG = −43.0 kJ/mol ATP → ADP + Pi ΔG = −30.5 kJ/mol What is the overall ΔG for the following Reaction? phosphocreatine + ADP → creatine + ATP A) -12.5 kJ/mol B) + 73.5 kJ/mol C) -73.5 kJ/mol D) + 12.5 kJ/mol
Consider the following reactions: #1: ATP + H2O -> ADP +P, #2: Phosphocreatine + H20 — #3: Phosphocreatine + ADP — creatine + P creatine + ATP (AG" =-31 kJ/mol) (4Gº = -43 kJ/mol) (AG'= -12 klimol) AG" for reaction #3 would be 12 km 0-12 kJimo 0 -43 kJimo 0 74 klimo
The formation of glucose-1-phosphate from glucose and orthophosphate has a G of + 20.9 kJ/mol. If this reaction were coupled to another reaction in order to produce an exergonic reaction, which of the following would produce an overall endergonic reaction and therefore not be suitable for coupling? A) creatine phosphate + H2O creatine + Pi B) AMP + H2O adenosine + Pi C) ATP + H2O AMP + PPi D) ATP + H2O ADP + Pi...
ATP + H2O <---> ADP + Pi Calculate the ΔG for ATP hydrolysis when the concentrations of ATP, ADP, and Pi are all 1M R = 1.98 x 10-3 T = 310 kelvin ΔGº = -30.5 kJ/mol
In the first step of glycolysis, the given two reactions are coupled. reaction 1: reaction 2: glucose +P: ATP + H2O glucose-6-phosphate + H,O + ADP + P AG = +13.8 kJ/mol AG = -30.5 kJ/mol Answer the four questions about the first step of glycolysis. Is reaction 2 spontaneous or nonspontaneous? O nonspontaneous O spontaneous Complete the net chemical equation. ATP+ + Calculate the overall AG for the coupled reaction. AG = kJ/mol Is the first step in glycolysis...
3. (3 pts) The following amination reaction is catalyzed by the enzyme alanine synthetase ADP + Pi + alanine ATP +pyruvate +NH3 Use the following equations with AG values given in kJ/mol to calculate AG for the overall reaction: ATP+H2O ADP + Pi Alanine+H2Opyruvate + NH3 (-30.5) (-6.0)
Shown is acetyl phosphate. Say a new enzyme uses acetyl phosphate to phosphorylate ADP to make ATP (acetyl phosphate + ADP —> acetate + ATP). What is the standard free energy change of this reaction? CH3 Table 13-2 Standard Free Energies of Phosphate Hydrolysis of Some Compounds of Biological Interest AGo (kJ mol 1) 61.9 -49.4 45.6 43.1 -43.1 30.5 -20.9 19.2 13.8 13.8 -9.2 Compound Phosphoenolpyruvate 1,3-Bisphosphoglycerate ATP AMP + PP,) Acetyl phosphate Phosphocreatine ATP ㈠ ADP + Pi)...
The enzyme hexokinase catalyzes the following reaction: Glucose + ATP ↔ Glucose 6-phosphate + ADP For this reaction, ΔG° = +16.7 kJ/mol a. Calculate the equilibrium constant for this reaction at 25 °C. Is this reaction spontaneous under standard conditions at this temperature? Calculate the ΔG if the reaction temperature was 25 °C and the concentrations are: glucose, 55.0 mM,; ATP, 5.00 mM; ADP, 1.00 mM; and glucose 6-Phosphate, 0.100 mM. Would the reaction be spontaneous under the conditions of...