help! thank you! Ibuprofen, a non-steroidal anti- inflammatory drug, is a weak acid with pKa of...
Ibuprofen, a well-known non-steroidal anti-inflammatory drug, has chirality. Only the S enantiomer has anti-inflammatory activity (although the R enantiomer is converted slowly by the body into the S enantiomer). Add wedge-and-dash bonds to complete the perspective structures of the two stereoisomers of ibuprofen.
(9 points) Starting from benzene, propose a synthesis of Ibuprofen a non-steroidal anti-inflammatory drug used for pain relief, fever reduction, and swelling OH Ibuprofen 16. (12 points) Provide a detailed (stepwise) mechanism for each of the following conversions: 1. CH, MgBr OED O + EtOH 2. H30, H20
1. Calculation of pH. A weak acid HA (pKa = 4.85) reacted with strong base NaOH The reaction is HA + NAOH H20 + NaA. There are 100 mL 0.100 M HA solution, and the concentration of Na OH is 0.100 M. 0 moles a. What is the pH when 0.00 mL of NaOH is added to the 100 mL HA solution? 2 x1 les b. What is the pH when 20.0 mL of NaOH is added to the 100...
PART A. Determine the pH of a 9.553 mM weak acid solution that has a pKa of 8.83 PART B. Calculate the pH of a 319 mM weak base solution with a pKb of 9.04. PART C. Determine the pKa of a weak acid solution that has an initial concentration of 0.334 M and a pH of 4.54. Hint: You know the pH of the solution, so you can easily determine x in your ICE table PART D. Calculate the...
A weak acid, HA, is partially titrated using NaOH. You start with 50.0mL of a 0.100 M HA and add 30.0 mL of a 0.100 M NaOH, and measure the pH of the solution at 7.00. What is the pKA of Ha? What would be the pH of the titration at the equivalence point (when 50.0 mL of NaOH is added)? I got the correct answer for the pKa (6.82), but don't know how to approach the second part. The...
Please help and show all work! 7. Ibuprofen is the active ingredient of the over-the-counter painkiller Advil. Its structure is shown below. Like other non-steroidal anti-inflammatory drugs, it works by inhibiting the synthesis of prostaglandins involved in the inflammation, pain, and fever pathway of the body. What is the Ka of ibuprofen if a 0.55 M aqueous solution of ibuprofen has a pH of 2.58 at 25°C? OH A. 1.45 x 10-3 B. 1.26 x 10-5 C. 7.31 x 10-7...
1" . I TV a OH Imagine you have a 0.125 M aqueous solution of aspirin, an acid drug with pKa = 3.5, in equilibrium. a) Estimate the pH of the solution Hint: Determine if it is an acid or base solution, weak or strong If weak acid/base, first try [H+] = VK.C, or [OH-] = /K,C, b) Predict what would happen to the pH when you add more H20 Hint: First figure out what happens to the concentrations HA(aq)...
thank you In the lecture we used titration of sodium carbonate with hydrochloric acid as an example to explain how to titrate a weak base with a strong acid. Suppose that you are using HNO3 to titrate Na3PO4, describe how to calculate pH at following different titration stages: (a) before titration (b) at 19 equivalence point (c) at 3rd equivalence point (d) between 2nd and 3rd equivalence points (e) after 3rd equivalence point Calculation is not required, simply write the...
It's a weak acid strong base titration Experiment 4: Identification of an unknown acid by titration Page 2 of 15 Background In this experiment, you will use both qualitative and quantitative properties to determine an unknown acid's identity and concentration. To do this analysis, you will perform a titration of your unknown acid sample-specifically a potentiometric titration where you use a pH meter and record pH values during the titration, combined with a visual titration using a color indi- cator...
can someone help me answer these 5 questions and figire this graph out please? Acid-Base Titration of a Weak Acid with a Strong Base: Determination of K. Introduction: You will be titrating a solution of a weak acid with 0.100 M NaOH, while monitoring the reaction using a pH meter. Weak acids have characteristic acid-ionization constants, K. The purpose of this lab is to use the titration to determine the value of this constant for the weak acid called “benzoic...