How do HCAs induce mutations?Heterocyclic amines (HCAs)
Discuss mechanisms by which gene expression may be altered. How do these alterations induce cancer-causing mutations in cell DNA? Explain how cancer is formed.
49. Name the Heterocyclic amines, (3 marks) a. b. N ining gosin orgid on and oil obim bu song months H 50. Draw the product formed from the following reaction. tbvod to bubong (3 marks) CH3 Heat fo H3C -OH + H2N- -CHE
What are two interesting properties of amines? How do these properties explain the solubility of amines in water? 7. Name each of the amine structures below AND indicate whether each is a primary, secondary or tertiary amine. 8. NH2 NH2 H2N B. NH
Both the lacIS and lacP- mutations result in the inability to induce expression of lacZ of lacY. You have recently isolated a mutant E,col with thie phenotype, and want to determine whether it is a new lacIS or lacP- mutant. Using whatever haploid or dipliod genotypes you want, describe a set of genotypes that would let you determine this. Explain reasoning.
How do non-synonymous mutations relate to synonymous mutations for positive vs purifying selection?
Assuming the heterocyclic ring above to be planar:Give the number of electrons that are contributed to the pi system of the heterocyclic ring by: How many electrons are in the pi system of the heterocyclic ring? (In the case of fused rings add all the pi electrons.) Is the heterocyclic ring with the numbered atoms aromatic?
1. You know that smoke from traditional cigarettes contains chemicals that can induce mutations. But what about e-cigarettes are they any safer than regular egarettes Describe how you would structure a study about electronic cigarettes and their effect on the incidence of lung cancer. Which type of study would be best case-controlled or randomized controlled? Forte A 2. Describe translation, induding where it takes place, the steps of the process, and the final products Portady For See BI A :...
How do mutations occur during transcription? Be specific.
chapter 18- amines and amides problem 18.87 part e <Chapter 18- Amines and Amides Problem 18.24 - Enhanced - with Feedback - Clinical Applications You may want to reference (Pages 634 637) Section 18.3 while completing this problem. Pyridoxine, which is also known as vitamin Bs, is found in many foods such as fish, boof, milk, and eggs, OH Pyridoxine Part A What is the heterocyclic amine in pyridoxine? Spell out the full name of the compound. Submit Request Answer...
Explain why primary and secondary amines form hydrogen bonds but tertiary amines do not?