14. The second step of glycolysis is the following reaction: Glucose-6-phosphate = Fructose-6-phosphate At pH 7...
9. One of the important reactions in the biochemical pathway glycolysis is the reaction of glucose-6-phosphate(G6P) to form fructose-6-phosphate (F6P): a) Is the reaction spontaneous or nonspontaneous under standard state conditions? b) Standard state conditions imply the concentrations of G6P and F6P to be 1 M, however, in a typical cell, they are not even close to these values. Calculate ΔG when the concentrations of G6P and F6P are 120 μM and 28 uM respectively, and discuss the spontaneity of...
The key step in the metabolism of glucose for energy is the isomerization of glucose-6-phosphate (G6P) to fructose-6-phosphate (F6P): G6P F6P K = 0.510, at 298K. Calculate Delta G when Q, the [F6P|/[G6P] ratio, equals 10.0. times 10 J/mol Enter your answer in scientific notation.
The second step of glycolysis is the conversion of glucose-6-phosphate to fructose-6-phosphate. What is the ΔG for this reaction at 25oC, when the glucose-6-phosphate] is 60 mM and the [fructose-6-phosphate] is 40 mM. Note: the ΔGo’ for this reaction is +1.7 kJ/mol (at 25oC). 0.780 kJ/mol 1.26 kJ/mol 1.47 kJ/mol 2.70 kJ/mol 0.695 kJ/mol 2.62 kJ/mol Answer not listed
Consider the given interconversion, which occurs in glycolysis. fructose 6-phosphate glucose 6-phosphate K1.97 What is AG for the reaction (K measured at 25 °C)? AG -1680.9 kJ/mol If the concentration of fructose 6-phosphate is adjusted to 1.4 M and that of glucose 6-phosphate is adjusted to 0.75 M, what is AG? AG =-4402.59 kJ/mol Which statements are consistent with the conditions at which AG is measured? The temperature is 273 K. The initial concentrations of reactant and product are 1...
The difference between AG and AG' (Basic Applied) In glycolysis the following reaction occurs: Fructose 6-phosphate Glucose 6-phosphate K'eq=1.97 a) What is the AGʻº for the reaction if K'eq is measured at 25°C? (2 points) b) If the concentration of fructose 6-phosphate is 1.5M and that of glucose 6-phosphate is adjusted to 0.50M what is AG? (3 points) c) Why are AG and AG' different? (1 point)
A highly regulated reaction in glycolysis involves the addition of a second phosphate to fructose-6-phosphate, which could be be written as: Fructose-6-phostphate + Pi à Fructose-1,6-bisphosphate + H2O The ∆Go’ for this reaction is +16.8 kJ/mol In a muscle cell at 37 oC, assume the concentration of Fructose-6phosphate is 0.014 mM and the concentration of phosphate is 1 mM. a. What would be the equilibrium concentration of fructose-1,6bisphosphate under these conditions? b. What is Keq for this reaction? Show...
1) SHOW WORK 12. During glycolysis, glucose 1-phosphate is converted to fructose 6-phosphate in two successive reactions: glucose 1-phosphate → glucose 6-phosphate glucose 6-phosphate + fructose 6-phosphate AG'' = -7.1 kJ/mol AG'º = +1.7 kJ/mol 13. The standard free-energy changes for the reactions below are given. phosphocreatine → creatine + Pi ATP → ADP + Pi AG" = 43.0 kJ/mol AG" = -30.5 kJ/mol What is the overall AG' for the following reaction? Iw a dee Hydrolysis of 1 M...
GLYCOLYSIS Glucose-8 phosphate + Glucose 2 Fructose-6-phosphate 3 Fructose-1,6-biphosphate Dihydroxy-acetone-phosphate 5 Glyceraldehyde-3-phosphate VT6 2 (1,3-biphosphoglycerate) 7 3-phosphoglycerate 2-phosphoglycerate 9 phosphoenolpyruvate 10 Lactate Pyruvate Which two reactions of glycolysis requires an investment of ATP energy, and which enzyme catalyzes each reaction? Reaction Number Enzyme Reaction Number Enzyme Which two reactions of glycolysis generate energy in the form of ATP, and which enzyme catalyzes each reaction? Reaction Number Enzyme Reaction Number Enzyme Which glycolytic reaction generates energy in the form of NADH,...
Glucose-6-P isomerase catalyses the following glycolytic reaction: Glucose-6-P (G6P) fructose-6-P G=1700 kJ/mol (Change in free energy) If 7.2 g of G6P* is dissolved in 980 mL of buffer and 150 µL of this is incubated with enzyme at 25°C & 37°C, what would be the equilibrium concentration of F6P at these two temperatures? [15 marks] *- The periodic table may be used to determine the molecular weight of G6P
In a cell, the concentration of glucose-6-phosphate is 83 μM and of fructose-6-phosphate is 14 μM. The ΔG°' = 410 cal/mol for the conversion of glucose-6-phosphate to fructose-6-phosphate. Assume the gas constant “R” is 1.987 and T is 298K. Based upon this information, the ΔG’ for this reaction (in cal/mol) is?