Question

Diagram the process of the proton Pump.

Mechanism of ATP Synthase NNNNNN ATP Synthase

Answer 1

ATP SYNTHASE ---

The use of proton motive force for ATP synthesis is catalysed by ATP synthase. The multi - protein ATP synthase or F0 F1 complex or complex v catalyzes ATP synthesis as protons flow back through the inner membrane down the electro-chemical proton gradient.It consist of two components -- F0 and F1 embedded in the inner mitochondrial membrane. F0 contains ''a'' subunits and 9-12 ''c'' subunits. Th c subunit consists of two alpha helices that span the membrane . An aspartic acid residue in the second helix lies on the centre of the membrane. F0 is a transmembrane complex that forms a regulated H+ channel . F 1 [made up of 3 alpha, 3 beta, gamma ,delta,and e ] is tightly bound to F0 and protudes into the matrix ;it contains three beta- subunits that are the sites of ATP synthesis.At the centre of F1 is the gamma-subunit .The gamma subunit extends through F 1 and interact with F0. The gamma E and C9-12 ring complex is the rotor [ moving unit ] and the a, b 2, alpha 3 beta 3 delta complex is the stator [ stationary unit ]. Rotational motion is impaired to the rotor by the passage of protons.The binding change mechanism is a widely accepted model of ATP synthesis.Paul boyer developed the binding change , or flip - flop mechanism ,which postulated that ATP synthesis is coupled with a conformational change in the ATP synthesis generated by rotation of the gamma subunit .

Matrix 7 Lipid bilayer Ic ICC I Inner mitochondrial membrane Inter Membrane Space. Scanned with CamScanner