Which of the following statements about xeroderma pigmentosum (XP) is FALSE? A. Mutations in one of...
Which of the following statements about xeroderma pigmentosum (XP) is FALSE?
| A. Mutations in one of several genes can contribute to the XP phenotype. | |
| B.The XP phenotype is caused by defects in double-stranded break repair pathways. | |
| C. XP patients are extremely sensitive to UV radiation in sunlight. | |
| D. Cells from XP patients are deficient in unscheduled DNA synthesis. |
Homework Answers
The correct answer is option B.
B.The XP phenotype is caused by defects in double-stranded break repair pathways.
Xeroderma pigmentosum is an autosomal recessive disorder. In this condition the ability to reapir the damaged DNA is deficient hence, they are sensitive to U.V light. This disease is present in both the genders of all races. The xeroderma pigemntosum is caused by the defects in the nucleotide excision repair pathways. Mutations in one of several genes can contribute to the XP phenotype. XP patients are extremely sensitive to UV radiation in sunlight. Cells from XP patients are deficient in unscheduled DNA synthesis.
Therefore, the option B. The XP phenotype is caused by defects in double-stranded break repair pathways.is false.
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