Question

Ul Ehé question paper. 1. Mutations can be caused by: a) tautomeric shifts b) UV light c) chemical changes to bases such as deaminatior C) all the above 2. The start of a wild type mRNA was AUGCCCAAGAccA mu tation This type of change resulted in the sequence AUGUCCAAGACC. is called a a) missense一®.frameshift mutation. 3. The typical rate of mutation for a human gene is per generation. a) 103 c) 10 d) 10-11 e) 104 4. If a hypothetical mutation left enzyme activity intact but changed an enzyme's substrate, the mutation was probably a AGmissense b) frameshift a) During base excision repair, a DNA glycosylase produces b) DNA polymerase III proofreads mutation 5. Which of the following is FALSE? apurinic or apyrimidinic site Photoreactivation repair removes part of the DNA sugar- phosphate backbone d) Xeroderma pigmentosum patients have a defect in t he nucleotide excision repair pathway. 6. In mismatch repair: a) either strand serves as template the enzyme identifies the correct template strand beca it is modified c) both DNA strands are deleted and the homologous chromosome is used as template 7. Which of the following genetically engineered products are available? a) Factor VIII c) tissue plasminogen activator (tPA) b) hepatitus B vaccine all of the above 8. Chromatin modifications: a) can be required in eukaryotes for gene expression b) can involve histone acetyltransferase enzymes (HAT) can relax the compact structure of chromatin all of the above

Answer 1

Mutations are caused by arousreasons.
The radiation by UV light, tautomeric shifts, and chemical changes like deaminaton cause mutations.
So option d is correct

THe mRNA sequence underwent a point mutation which is a missense mutation.
Option a is correct