Question

13) The number of new mutations in a given gene per cell generation is called? B) mutation rate C) recombination frequeney 14) A type of spontaneous mutation that occur when a purine base is removed from the DNA is A) deamination D) alkylate bases В) apurination E) base analog C) thymine dimers 15) A type of spontaneous mutation that involves a temporary change in the base conformation because the keto group may change to an enol functional group or amino to immino prior to DNA replication is IS. A) tautomeric shift E) t B) deamination C) x-rays D) uv rays e elemen 16) A type of spontaneous mutation that occur from the removal of an amino group from the cytosine base resulting to a uracil base is A) deamination D) alkylate bases B) apurination C) thymine dimers E) base analog 17) This technique can be used to locate the position of a gene at a particular site within an intact chromosome. A) Ames test B) Western blot C) Fluorescence in situ hybridization D) DNA sequencing E) Linkage mapping 18) This repair system uses photolyase enzyme activated by light to repair thymine dimers in E. coli C) Mismatch repair A) Nucleotide excision repair B) Base excision repair ) Direct repair E) Homologous recombination 19) This repair system uses DNA N-glycosylase to recognize uracil base in the DNA molecule C) Mismatch repair A) Nucleotide excision repair B) Base excision repair D) Direct repair E) Homologous recombination 20) This repair system uses sister chromatids as template to correct the double strand breaks in DNA C) Mismatch repa A) Nucleotide excision repair B) Base excision repair D) Direct repair E) Homologous recombination 21) The0 in a population? for a gene is the number of mutant genes divided by the total number of B) mutation rate C) recombination frequ A mutation frequency D) co transduction frequency E) co-transformation frequency

Answer 1

Q.13 – Option B.

Mutation rate is the average number new mutation which are generated in a gene per cell generation.

Q.14 – Option B.

Depurination is a process where a purine base is removed from the DNA.

Q.15 – Option A.

A temporary change in base conformation from enol to keto is known as tautomeric shift.

Q.16 – Option A.

Removal of amino group from the bases are known as deamination.

Q.17 – Option C.

Fluorescent in situ hybridisation can bind to the specific sequence in a chromosome with high level of complementarity.

Q.18 – Option A.

When the damaged nucleotide is replaced with the new one it is known as nucleotide excision repair. This repair mechanism is generally used during pyrimidine dimer formation.

Q.19 – Option B.

In base excision repair the N-glycosidic between base and deoxyribose sugar is hydrolysed. Then the base is replaced with the new one.

Q.20 – Option E.

During a double strand DNA break, the cell repairs it by means of homology directed repair.

Q.21 – Option A.

Mutation frequency is the ratio of mutant divided by total cells in a population.