QUESTION 11 does not require supplemental histidine). True or False: Using the Ames test, a compound...
QUESTION 11 does not require supplemental histidine). True or False: Using the Ames test, a compound is determined to be mutagenic if it causes a His bacterial strain (requires histidine in the growth medium) to become His O True False QUESTION 12 Xeroderma pigmentosa (XP): is caused by a defect in the mismatch repair system. O typically results in base substitution mutations. can be caused by defects in any of a number of different genes that have to do with DNA repair. O results when an individual does not spend enough time outside. can be corrected by a direct repair mechanism. QUESTION 13 How does E. coli determine which nucleotide to "fix" in a base mismatch? The appropriate DNA repair system: recognizes fully methylated DNA and replaces the purine. O recognizes partially methylated DNA and replaces the pyrimdine. recognizes partially methylated DNA and fixes the methylated strand. recognizes partially methylated DNA and fixes the nonmethylated strand. makes no distinction between strands, and therefore fixes the wrong base 50% of the time. QUESTION 14 Match the E. coli mismatch repair enzyme on the left with the appropriate function on the right. 1. Mut s 2. Mut a. facilitates the looping of the region of DNA to be replaced b. distinguish between parental and newly-synthesized DNA c. locates mismatches in the DNA mi Mut OOOOO Dini Di U O D mmmmm 16 U DO i