Question

EMT= epithelial-mesenchymai transition

MET= mesenchymal-epithelial transition

Answer each in 5-8 sentences please.

1) How are EMT and MET similar? How are they different? 2) In reference to cancer metabolism, what is the Warburg effect? 3) Why is angiogenesis an essential step for most cancer progression? 4) What is the most prevalert for of cancer? Hint think about the tissue type it originates fr ). How is it called when it arises form cells that had a secretory function? Gwe an example for each. F2 딤o,3 8238 F4 11 3 O D G )0 (9 *8 U &7 H 6 %5 $4

Answer 1

EMT Rightarrow degree Its a process by which epithelial cells lose their cell polarity & cell - cell adhesion, & gain migratory & properties to become mesenchymal stem cells. It is essential for numerous developmental process including mesodexm formation & neural tube formation MET Rightarrow It is a reversible biological process that involves the transition from, multiplex or spindle - shaped mesenchymal cells to planax arrays of polarized cells cla epithelia. Its a reverse process of EMT. METs occur in normal development, cancel metostasis & induced pluripolent stem cells reprogramming.