Question

1) Describe the type of morph youd expect from the neo-stop allele and explain your reasoning. 8 Loxp2 neo-stop Loxp1 9 10 11 12 Note: The above figure is a neo-stop allele, that is the product of engineering the FGFR3 locus. The transmembrane domain is coded for in exons 9 and 10 and the kinase domain is in 11 and 12.

0 0
Add a comment Improve this question Transcribed image text
Answer #1

The morph we do expect from this will be as follows:

8 Loxp 9 10 12

due to targeting construction, the the neo stop will be removed with the help of FLP recombinase followed by the 2 step recombination between loxP sites resulting into the active morph with direction as shown in diagram.

Add a comment
Know the answer?
Add Answer to:
1) Describe the type of morph you'd expect from the neo-stop allele and explain your reasoning....
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for? Ask your own homework help question. Our experts will answer your question WITHIN MINUTES for Free.
Similar Homework Help Questions
  • i need help with all of these. please. The center-to-center distance from reference hole A to...

    i need help with all of these. please. The center-to-center distance from reference hole A to hole B is 3.00"+/-0.11". Hole A will be (4.0/-0.1"). If a jig is to be used to locate hole B by inserting a locator pin in hole A of o(3.85+/-0.05"), due to the slack between the jig locator pin and hole A: What are the potential limits in the location of hole B? b. Are these potential limits acceptable? c If the potential limits...

  • For each question below select the best answer from those listed and give your reasoning. Your...

    For each question below select the best answer from those listed and give your reasoning. Your reasoning need only be a sentence or two. It is not enough to get the right answer, you must know why it is the right answer. Question 5 Fred's friend claimed that Canadians tend to be jerks. Fred wondered if that was true, and tested it by checking to see how many Canadian jerks he could think of. Fred's cognitive strategy is             ["the availability...

  • 1. find an article about a product or service that impacts your daily life and write...

    1. find an article about a product or service that impacts your daily life and write 1 to 2 paragraphs describing the item, how it impacts your life, and what factors you think are impacting the supply and demand of this item. Be sure to include the URL of the article you accessed for this question. 2.What are the ethics of outsourcing? Is a corporation’s primary responsibility to its stockholders, by reducing labor costs? Or is its primary responsibility to...

  • 9. Then add slowly while mixing 1 mL of saturated sodium bicarbonate solution (NaHCO3) -IT WILL...

    9. Then add slowly while mixing 1 mL of saturated sodium bicarbonate solution (NaHCO3) -IT WILL BUBBLE! Add additional drops of saturated sodium bicarbonate solution with mixing until no additional bubbling occurs Congratulations! You have just made your first ester. Now you want to separate your ester product from the other stuff in the reaction mixture. CTQ3 Sodium bicarbonate is a base. How will it interact with any carboxylic acid molecules still present in your reaction mixture? 10. Add 1mL...

  • Background Jeraldine Yates is a 70-year-old woman originally from Alabama. She lives alone and is able to manage herself...

    Background Jeraldine Yates is a 70-year-old woman originally from Alabama. She lives alone and is able to manage herself independently. She is active in her community and church. Mrs. Yates was admitted to the hospital two months ago with heart failure. Since her discharge, a visiting nurse visits every other week to assess for symptoms of heart failure and see that Mrs. Yates is continuing to manage well on her own. Case Study The visiting nurse stops in to see...

  • Background Jeraldine Yates is a 70-year-old woman originally from Alabama. She lives alone and is able...

    Background Jeraldine Yates is a 70-year-old woman originally from Alabama. She lives alone and is able to manage herself independently. She is active in her community and church. Mrs. Yates was admitted to the hospital two months ago with heart failure. Since her discharge, a visiting nurse visits every other week to assess for symptoms of heart failure and see that Mrs. Yates is continuing to manage well on her own. Case Study The visiting nurse stops in to see...

  • e. 18 Test Your Knowledge MULTIPLE CHOICE: Choose the one best answer. 1. Each element has...

    e. 18 Test Your Knowledge MULTIPLE CHOICE: Choose the one best answer. 1. Each element has its own characteristic atom in which a. the atomic mass is constant. b. the atomic number is constant. c. the mass number is constant. d. Two of the above are correct. e. All of the above are correct. 2. Which of the following is not a trace element in the human body? a. iodine b. zinc c. iron d. calcium e. fluorine 3. A...

  • Impulse and Momentum Name: Date: TA's Name: Learning Objectives: 1. Understanding force ys time curves for...

    Impulse and Momentum Name: Date: TA's Name: Learning Objectives: 1. Understanding force ys time curves for a collision. 2. Calculating impulse using force vs. time curves. 3. Understanding the relationship between impulse and momentum. 4. Applying conservation of momentum for inelastic collisions. Apparatus: Aluminum track, track legs, two smart carts, two cart stops, and small black rectangular cart masses. Part A: Collision of a moving cart with a fixed cart cart 1 Cart stop stationary cart cart stop Consider the...

  • 1. According to the paper, what does lactate dehydrogenase (LDH) do and what does it allow...

    1. According to the paper, what does lactate dehydrogenase (LDH) do and what does it allow to happen within the myofiber? (5 points) 2. According to the paper, what is the major disadvantage of relying on glycolysis during high-intensity exercise? (5 points) 3. Using Figure 1 in the paper, briefly describe the different sources of ATP production at 50% versus 90% AND explain whether you believe this depiction of ATP production applies to a Type IIX myofiber in a human....

  • Data Analysis Project Part 1 Custom Fabric Ventures is a small company that produces fabric-based wardrobe...

    Data Analysis Project Part 1Custom Fabric Ventures is a small company that produces fabric-based wardrobe accessories (such as, handbags, scarves, and headbands) and home accessories (such as placemats, pillows, and window treatments).   The company keeps a limited number of popular items in stock, but primarily produces custom orders. Customers are able to choose from a wide selection of styles, sizes, and fabrics for each type of product. Most of the company’s customers are small boutiques, home décor shops, and home-decorators...

ADVERTISEMENT
Free Homework Help App
Download From Google Play
Scan Your Homework
to Get Instant Free Answers
Need Online Homework Help?
Ask a Question
Get Answers For Free
Most questions answered within 3 hours.
ADVERTISEMENT
ADVERTISEMENT
ADVERTISEMENT