Below are listed some steady-state concentrations of the intermediates of glycolysis in the human erythrocyte. Very...
1. You have given all the enzymes and intermediates in glycolysis. Choose the right enzymes and intermediates and draw the glycolytic pathway. Decorate the diagram by adding ATP, ADP, H", NADH, NAD', P, and H20 where necessary. All the steps are reversible except 1, 3 and 10; draw appropriate arrow. First arrange the reactants in the correct order. Reactants/intermediates: 3-phosphoglycerate glucose Phosphoenolpyruvate dihydroxyacetone phosphate Pyruvate glucose 6-phosphate 1,3-bisphosphoglycerate fructose 6-phosophate 2-phosphoglycerate glyceraldehyde 3-phosphate fructose 1,6-bisphosphate Enzymes: Phosphoglucoisomerase phosphoglycerate kinase phosphoglycerate...
and Q. Many metabolites are maintained at steady-state concentrations that are far from equilibrium. A comparison of K the mass-action ratio, can determine whether a metabolic reaction is far from equilibrium. The equation for this equilibrium is, fructose 6-phosphate + ATP fructose 1,6-bisphosphate + ADP Calculate for this reaction at T = 25.0°C. AG = -14.2 kJ/mol K Calculate the mass-action ratio, Q. from the approximate physiological concentrations for rat heart tissue shown in the table. Q Metabolite fructose 6-phosphate...
Concentrations of some glycolysis intermediates in the red blood cell (mM): Glucose Glucose-6-P Fructose-6-P Fructose-1,6-BP 1,3-bisphosphoglycerate 0.001 3-phosphoglycerate 5.0 0.083 0.014 0.031 2- phosphoglycerate Phosphoenolpyruvate Pyruvate ATP ADP Pi 0.030 0.023 0.051 1.85 0.14 1.0 0.12 3. Isotopic labeling (incorporating a rare isotope, eg. the radioactive 1C, into a molecule at a defined position) is an important technique for studying metabolism as it enables us to follow individual atoms through a metabolic pathway 2 a. If 4CO2 were bubbled through...
12/25 answered Click on glycolysis if would like to review it in details. Glucose Preparatory phase first ATP Phosphorylation of glucos and its conversion to glyceraldehyde 3-phosphat Priming © > ADP Glucose 6-phosphate 1-0 Hz Hexokinase ΝΟΗ Η e Phosphohexose isomerase Fructose 6-phosphate ATP (8 Phospho- fructokinase-1 primins и он -OCH, CH-OH HOH он и ©--CH, CH-0- Кинон Aldolase ADP Fructose 1,6-bisphosphate (6) Triose phosphate somerase eleava oferte suar phosphate to two carbon sur phosphate Glyceraldehyde 3-phosphate udehyde a phosphate...
1. According to the paper, what does lactate dehydrogenase
(LDH) do and what does it allow to happen within the myofiber? (5
points)
2. According to the paper, what is the major disadvantage of
relying on glycolysis during high-intensity exercise? (5
points)
3. Using Figure 1 in the paper, briefly describe the different
sources of ATP production at 50% versus 90% AND explain whether you
believe this depiction of ATP production applies to a Type IIX
myofiber in a human....