Homework Answers
1) Assuming that autoregulation is not working we can conclude that in the presence of higher than normal levels of plasma proteins than it will lead to a decrease in glomerular filtration rate.
2) GFR would change this way because of the following reason:
The proteins provide oncotic pressure on the glomerulus. Basically oncotic pressure functions to hold water back in the glomerulus under normal conditions. No protein should be filtered by glomerulus which means that protein are absent in the Bowman's space. However, when the level of protein rises than normal then the oncotic pressure comes into play and tries to hold water back. This is the reason that rate of GFR is decreased. Also when level of protein increases then it causes inflammation as well as scarring in the renal tubules which leads to subsequent nephron loss.
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If a person drinks a large amount of water very quickly, it is possible to exceed...
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possible to exceed the rate of water removal by the kidney (~1
L/hour), essentially diluting the blood. The resulting osmotic
pressure causes cells to swell. Fat and muscle cells have a
capacity to adjust to this change in volume, but neurons in the
brain do not have room to accommodate this size increase. (The
skull is so densely packed, there is no room for swelling!)
Consequently, as...
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If a person drinks a large amount of water very quickly, it is
possible to exceed the rate of water removal by the kidney (~1
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pressure causes cells to swell. Fat and muscle cells have a
capacity to adjust to this change in volume, but neurons in the
brain do not have room to accommodate this size increase. (The
skull is so densely packed, there is no room for swelling!)
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