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Marijuana disrupts memory via effects on:

Marijuana disrupts memory via effects on:

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  • Marijuana disrupts short-term memory..The drug impairs users’ working memory — the ability to retain and use information over short periods of time.This common side effect occurs because of a previously unknown signalling mechanism between neurons and non-neuronal cells called astrocytes.
  • The psychoactive ingredient of marijuana is tetrahydrocannabinol (THC). Using microelectrodes implanted into the brains of anaesthetized rats, the researchers found that the compound weakens the connections, or synapses, between neurons in the hippocampus, a structure that is crucial for memory formation.
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