Question

1. A common notation for the depiction of binding events in a multi-substrate enzyme is to show the enzyme as a horizontal li
0 0
Add a comment Improve this question Transcribed image text
Answer #1

Glucose 61-6-0 ATP ADP E+GI EIGI + ATP E+ G1-60 - ADP E 6. Gl-6-0

G3-P NAD, si NADH Bla 6.6 3-1 E.G-3-P. NAD.Pi - → E. BPG. NADH E.BG

Justification for a and b.

Horizontal line presentation is based on the sequence of binding of substrates with enzymes and vice versa (i.e. Release of products from enzyme).

In the first case, the sequence of events is well defined in the question. Firstly, enzyme will bind to glucose and then binding of ATP will take place. Subsequently, conversion will take place resulting in formation of glucose 6 phosphate. The release sequence is also defined in the question with ADP release happening before dissociation of enzyme and glucose 6 phosphate.

In the second case, sequence of events is not provided. Thus, the binding of substrate with enzyme is predicted based on affinity and energy kinetics. First, binding of enzyme with substrate will take place which further allows the binding of NAD and inorganic phosphate. Subsequently, conversion of substrate into NADH and BPG will occur. The dissociation of NADH will take place followed by BPG resulting in release of enzyme.

Add a comment
Know the answer?
Add Answer to:
1. A common notation for the depiction of binding events in a multi-substrate enzyme is to...
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for? Ask your own homework help question. Our experts will answer your question WITHIN MINUTES for Free.
Similar Homework Help Questions
  • 29. The activity of the enzyme phosphofructokinase is a) stimulated by low energy charge b) inhibited...

    29. The activity of the enzyme phosphofructokinase is a) stimulated by low energy charge b) inhibited by fructose 2,6-bisphosphate c stimulated by fructose 1.6-bisphosphate d) all of the above 30. NADH is produced at a) aldolase catalyzed reaction b) Glyceraldehyde-3-phosphate dehydrogenase catalyzed reaction c) pyruvate kinase catalyzed reaction d) hexokinase catalyzed reaction 31. The transfer of 3-phosphoglycerate to 2-phosphoglycerate is catalyzed by which enzyme? a) PGM b)PK c)G2PDH d)TPI e)PFK 32. The enzyme aldolase catalyzes which reaction in Glycolysis? a)...

  • Match the enzyme to the substrate --> product reaction to which it catalyzes. O Hold and...

    Match the enzyme to the substrate --> product reaction to which it catalyzes. O Hold and drag to reorder Phosphoglycerate Mutase Glucose --> Glucose 6-phosphate Phosphohexose Isomerase 1-3- Bisphosphoglycerat e--> 3- Phosphoglycerate Hexokinase Fuctose 1-6- bisphophate --> Glyceraldehyde 3- phosphate + Dihydroxyacetone phosphate Phosphoglycerate Kinase Oxaloacetate --> Phosphoenolpyruva te Aldolase Mannose 6- phosphate -> Fructose 6- phosphate Pyruvate kinase Dihydroxyacetone phosphate -> Glyceraldehyde 3- phosphate Enolase Glyceraldehyde 3- phosp Bisph Submit Glyceraldehyde 3- phosphate Enolase Glyceraldehyde 3- phosphate -> 1-3-...

  • 1. Diagram the process of sucrose breakdown into glucose and fructose and submit as an image. Use...

    1. Diagram the process of sucrose breakdown into glucose and fructose and submit as an image. Use Worksheet 7 to illustrate this process (Show structures and enzymes. Include any key intermediates). 2. Diagram the process of fructose is metabolized into glycolysis in adipose tissue and submit as an image. Use Worksheet 7 to illustrate this process (Show structures and enzymes. Include any key intermediates) 3. Diagram the process of fructose is metabolized into glycolysis in liver tissue and submit as...

  • 1. You have given all the enzymes and intermediates in glycolysis. Choose the right enzymes and...

    1. You have given all the enzymes and intermediates in glycolysis. Choose the right enzymes and intermediates and draw the glycolytic pathway. Decorate the diagram by adding ATP, ADP, H", NADH, NAD', P, and H20 where necessary. All the steps are reversible except 1, 3 and 10; draw appropriate arrow. First arrange the reactants in the correct order. Reactants/intermediates: 3-phosphoglycerate glucose Phosphoenolpyruvate dihydroxyacetone phosphate Pyruvate glucose 6-phosphate 1,3-bisphosphoglycerate fructose 6-phosophate 2-phosphoglycerate glyceraldehyde 3-phosphate fructose 1,6-bisphosphate Enzymes: Phosphoglucoisomerase phosphoglycerate kinase phosphoglycerate...

  • 000000 5. Some bacteria make an enzyme that can convert dihydroxyacetone to dihydroxyacetone phosphate (DHAP). How...

    000000 5. Some bacteria make an enzyme that can convert dihydroxyacetone to dihydroxyacetone phosphate (DHAP). How would this help these cells yield energy? Hint: look at the diagram of glycolysis to the right Glucose Ister Unstable 0000000- Fructose-1,6-bisphosphat DHAP glyceroldehyde- • 3-phosphate - -- - - - - - All the DHAP MAD, will be converted into gyaraldehyde RAM 3-phosphate ADP Happens Pyruvate 6. If a cell respiring on glucose runs out of oxygen and/or other electron acceptors, what happens...

  • I am confused with this glucose structure, Can you answer the question asked on the right...

    I am confused with this glucose structure, Can you answer the question asked on the right side of the page, please? Glucose Hexokinase ATP Glucose 6-phosphate Phosphoglucose isomerase Fructose 6-phosphate Phosphofructo- ATP kinase-1 ADP Dihydroxyacetone phosphate Fructose 1,6-bisphosphate Aldolase Triose 5 phosphate Glyceraldehyde isomerase 3-phosphate (2 molecules ) Glyceraldehyde 2 NAD+ +2P, 3-phosphate 2 NADH + 2H dehydrogenase I 1,3-Bisphosphoglycerate (2 molecules) 7 Phosphoglycerate 2ADP kinase 2 ATP 3-Phosphoglycerate (2 molecules) Phosphoglycero- mutase 2-Phosphoglycerate (2 molecules) Enolase. > 2H2O Phosphoenolpyruvate...

  • Rank from the first to the last steps to describe the correct order of events of...

    Rank from the first to the last steps to describe the correct order of events of glycolysis. Rank from the first to the last steps to describe the correct order of events of glycolysis. Reset Help Glyceraldehyde- 3-phosphate COOP 3-phosphoglycerate ooo ATP This reaction happens Glucose-6-phosphate OOOOOO Rearrangement P + ADP Glucose GOOOOO NAD* - Fructose-16-bisphosphate POOOOOO twice, once ADP for each glyceraldehyde- 3.phosphate bisphosphoglycerate OOOP + NADH Fructose-6-phosphate ССССССР 2-phosphoglycerate This GOO reaction happens Rearrangement twice, once Phosphoenolpyruvate for...

  • 1. 2. 3. 4. Select all that apply. Identify the reaction(s) of glycolysis inhibited by ATP □ glyceraldehyde-3-phosphate → 1,3-bisphosphoglycerate phosphoenolpyruvate +pyruvate 3-phosphoglycerate...

    1. 2. 3. 4. Select all that apply. Identify the reaction(s) of glycolysis inhibited by ATP □ glyceraldehyde-3-phosphate → 1,3-bisphosphoglycerate phosphoenolpyruvate +pyruvate 3-phosphoglycerate ~2-phosphoglycerate 1) fructose-6-phosphate→ fructose-1,6-bisphosphate . glucose glucose-6-phosphate Select all that apply. Alcohol fermentation: consumes ATP as it produces ethanol. O produces carbon dioxide begins as pyruvate is decarboxylated to acetaldehyde in a reaction catalyzed by alcohol dehydrogenase m regenerates NAD requires the enzyme alcohol dehydrogenase, In the figure below, what is the reaction occurring at the location...

  • vou 15 watch the video Chapter 11 - Earyme Classification Worksheet 1 Enurymes are classified by...

    vou 15 watch the video Chapter 11 - Earyme Classification Worksheet 1 Enurymes are classified by reaction type as follows: TALE E Classical Classification 1. Owideductase 2. Transferases 3. Hydrolases 4. lyases 6. Ligas hydrolysis SO 70 Using your previous knowledge in organic chemistry, match the following reactions with their corresponding classification. Reaction 1: Reaction 2: Dihydroxyacetone OO phosphate (DHAP нсон + ADP CHOP: CH,OPO) CHOPO" HOCH 1,3-Bisphosphoglycerate (1,3 BPG) HOSH aldelas N-S-OH phosphoglycerate My! Ho kinase (PGK) A -H...

  • 6. In question 5, what is the most important reaction involved in formation of lactate? A)...

    6. In question 5, what is the most important reaction involved in formation of lactate? A) dihydroxyacetone phosphate glycerol 3-phosphate D) pyruvate → lactate B) oxaloacetate → malate E) isocitrate → a-ketoglutarate C) glucose 6-phosphate → fructose 6-phosphate 7. During the process in question 5 (the rapid rise in lactate concentration), the NADH must be reoxidized to NAD+. Which of the following enzymes will be most affected if NADH is not reoxidized? A) Pyruvate kinase. C) Phosphofructokinase-1. E) aldolase. B)...

ADVERTISEMENT
Free Homework Help App
Download From Google Play
Scan Your Homework
to Get Instant Free Answers
Need Online Homework Help?
Ask a Question
Get Answers For Free
Most questions answered within 3 hours.
ADVERTISEMENT
ADVERTISEMENT
ADVERTISEMENT