What is deamination and how do cells repair this kind of damage?
What is deamination and how do cells repair this kind of damage?
Homework Answers
The most usual source of DNA damage is the process of Deamination.
Deamination of DNA nucleic bases is defined as the spontaneous loosing of amino group (-NH2) and finally result in unusual and abnormal bases.
Base excitsion repair is used by the cells in this mechanism the damaged cellular distorting, non-helix, DNA base lesions removed by several enzymes such as glycosylase and endonuclease. For example Spontaneous deamination is nothing but the hydrolysis of thymine to uracil which can be repaired by glycosylase enzyme through base excision repair.
Discuss the following statement: The DNA repair enzymes that correct damage introduced by deamination and depurination...
Discuss the following statement: The DNA repair enzymes that correct damage introduced by deamination and depurination must preferentially recognize such defects on newly synthesized strands.
What kind of damage is frequently caused and how does photolyase repair the damage? Drag the...
What kind of damage is frequently caused and how does photolyase repair the damage? Drag the terms on the left to the appropriate blanks on the right to complete the sentences. Not all terms will be used. Reset Help abnormal structures UV irradiation causes the formation of called by causing the formation of DNA. Photolyase uses the energy of visible light to chemical bonds opposite bases duplications fix these mutations adjacent bases photopeptides break those bonds photoproducts deletions of between...
Q1: If DNA damage occurred, the cells repair the damage by several mechanisms during the cell...
Q1: If DNA damage occurred, the cells repair the damage by several mechanisms during the cell cycle. In which phase of the cell cycle cells will repair the damage? Name five of the repair mechanisms that cells are using to repair DNA damage? What are the repair mechanism for double strand DNA breaks? Describe them and Which of them is the error- free repair pathway?
How and what kind of cells deal with telomere shorterning? How do some cells resolve the...
How
and what kind of cells deal with telomere shorterning?
How do some cells resolve the problem of telomere shortening? What kinds of cells usually do this?
Repair of DNA damage from UV radiation DNA damage from UV radiation needs to be repaired...
Repair of DNA damage from UV radiation
DNA damage from UV radiation needs to be repaired if
DNA replication occurs without error. the following plot shows how
cell survival is affected in the presence of UV radiation. Notice
that the wild-type cells can overcome the damaging effects of UV
radiation on DNA and show high survival even as UV increases.
However, cells deficient in certain genes display relatively much
lower survival rates.
1. the fact that the double mutant shows...
9. Shown below is a list of types of repair systems or repair molecules (a-d) and...
9. Shown below is a list of types of repair systems or repair molecules (a-d) and types of DNA damage or mutations (1-4). On the blank line following each type of damage, write the letter(s) of all repair systems that can repair that particular type of damage. a) Direct repair b) Base-excision repair c) Double-strand break repair d) Nucleotide-excision repair 1) Lesions caused by intercalating agents __________ 2) Pyrimidine dimers B 3) Deamination __________ 4) X-ray damage to chromosomes __________
2. Oxidation of nitrogenous bases is one type of DNA damage. a. What is the most...
2. Oxidation of nitrogenous bases is one type of DNA damage. a. What is the most common mechanism for repairing oxidized bases? (1 mark) b. Outline the steps involved in the mechanism you listed in part (a). (3 marks) C. How is this mechanism able to repair other types of damaged bases (for example, deamination of cytosine)? (1 mark)
What are the "basic" cells, what kind of tissues do they make? and where are some...
What are the "basic" cells, what kind of tissues do they make? and where are some places in the body can they be found.
Photoreactivation is called a direct reversal of DNA damage. Mismatch repair, Nucleotide excision repair and base...
Photoreactivation is called a direct reversal of DNA damage. Mismatch repair, Nucleotide excision repair and base excision repair correct DNA mismatches and damaged bases, but these systems are not considered direct repair. what two general steps do these indirect repair systems have in common?.
Question 2 3 pts AP (apurine or apyrimidine) site is a result of what kind DNA...
Question 2 3 pts AP (apurine or apyrimidine) site is a result of what kind DNA damage? Thymine-thymine dimer. Adenine Guanine mismatch error. Cytosine to Uracil deamination. O ionizing radiation.
What kind of damage is frequently caused and how does photolyase repair the damage? Drag the terms on the left to the appropriate blanks on the right to complete the sentences. Not all terms will be used. Reset Help abnormal structures UV irradiation causes the formation of called by causing the formation of DNA. Photolyase uses the energy of visible light to chemical bonds opposite bases duplications fix these mutations adjacent bases photopeptides break those bonds photoproducts deletions of between...
How
and what kind of cells deal with telomere shorterning?
How do some cells resolve the problem of telomere shortening? What kinds of cells usually do this?
Repair of DNA damage from UV radiation
DNA damage from UV radiation needs to be repaired if
DNA replication occurs without error. the following plot shows how
cell survival is affected in the presence of UV radiation. Notice
that the wild-type cells can overcome the damaging effects of UV
radiation on DNA and show high survival even as UV increases.
However, cells deficient in certain genes display relatively much
lower survival rates.
1. the fact that the double mutant shows...
2. Oxidation of nitrogenous bases is one type of DNA damage. a. What is the most common mechanism for repairing oxidized bases? (1 mark) b. Outline the steps involved in the mechanism you listed in part (a). (3 marks) C. How is this mechanism able to repair other types of damaged bases (for example, deamination of cytosine)? (1 mark)
Question 2 3 pts AP (apurine or apyrimidine) site is a result of what kind DNA damage? Thymine-thymine dimer. Adenine Guanine mismatch error. Cytosine to Uracil deamination. O ionizing radiation.
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