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Discuss the following statement: The DNA repair enzymes that correct damage introduced by deamination and depurination...

Discuss the following statement: The DNA repair enzymes that correct damage introduced by deamination and depurination must preferentially recognize such defects on newly synthesized strands.

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DNA damage by deamination and depurination reactions occur spontaneously . This type of damage is equally likely to occur on either strand and these damages are not the result of an replication errors. If the DNA repair enzymes recognized damages only on the newly synthesized DNA strands half of the defects would go uncorrected. Therefore the statement is incorrect.

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