Which of the following statement regarding cyclins IS NOT CORRECT?
Which of the following statement regarding cyclins IS NOT CORRECT? When a cell moves through a...
Dynamic phosphorylation/dephosphorylation is key to proper cell cycle control in that: (select all answers that apply) A. CAKs phosphorylate (and activate) CDK subunits. B. Wee1 kinase phosphorylates (and activates) CDK subunits. C. Cdc25 kinase phosphorylates (and activates) CDK subunits. D. Phosphorylation of the CKI Sic1 directs its subsequent ubiquitination and proteasomal degradation. E. Kinases phosphorylate (and activate) SCF, the ubiquitin ligase responsible for degradation of G1/S phase cyclins.
9. In human cells four different cyclins drive the cell cycle (see picture). Please, note that the cyclins overlap (the picture shows the concentration of each cyclin protein in the cytoplasm). Write a short essay or outline of an experiment to test the following things: How can you figure out how much cyclin protein is present in the cytoplasm at different phases of the cell cycle? B. How can you figure out if there is overlap between the cyclins? For...
Question 1 3 pts One Cdks are _whose activity is regulated throughout the cell cycle, such that! method of inhibition is accomplished by phosphatases, it is high in Sphase but low in mitosis, increased transcription of cyclins kinases, it is low in G1 but increases exponentially throughout the cell cycle until anaphase, phosphatases such as Cdc25 O kinases, it is high as the cell enters S and M phases but decreases at the end of mitosis, restricted transcription of cyclins...
Which of the following statements is true regarding cell cycle regulators? Choose 1 answer: Different cyclins send a Cdk to different targets. Levels of cyclins do not change dramatically across the cell cycle. When a cyclin partners with a Cdk, it inactivates the Cdk. A Cdk is a DNA repair enzyme.
4. Short response (2 sentences max, 6pts each) A. Many yeast species have only one cyclin-dependent kinase (Cdk), which activates protein targets that drive events in multiple phases of the cell cycle. Why doesn't this Cdk activate G1-, S-, G2-, and M-phase proteins all at the same time? B. Please describe how cell death by apoptosis can play a beneficial role in the body's healthy growth. C. For a cell starting in G1, place the following cell cycle events in...
4. Short response (2 sentences max, 6pts each) A. Many yeast species have only one cyclin-dependent kinase (Cdk), which activates protein targets that drive events in multiple phases of the cell cycle. Why doesn't this Cdk activate G1-, S-, G2-, and M-phase proteins all at the same time? B. Please describe how cell death by apoptosis can play a beneficial role in the body's healthy growth. C. For a cell starting in G1, place the following cell cycle events in...
Which of the following statements is correct regarding the events of the cell cycle? The M phase is usually the longest phase. Interphase consists of G1, S, and G2. DNA is duplicated during the G1 and G2 phases. DNA replicates during cytokinesis.
QUESTION 1 A gene that encodes a protein that stimulates progression of the cell cycle is known as a proto-oncogene. True False QUESTION 2 Cytokinesis occurs after which stage or phase of the cell cycle? a. G2 b. S c. G0 d. G1 e. M phase QUESTION 3 During cell-cycle checkpoints, protein kinases known as CDKs phosphorylate target proteins only when they associate with a cyclin. True False QUESTION 4 During mitosis, many of the spindle fibers attach to chromosomes...
6.) Mitogens are (b) transcription factors important for cyclin production (c) kinases that cause cells to grow in size (a) extracellular signals that stimulate cell division. d) produced by mitotic cells to keep nearby neighboring cells from dividing 7.) Which of the following cyclins is most active during mitosis? (a) cyclin A (b) cyclin B (c) cyclin C (d) cyclin D 8) Which molecule inactivate itotic cyclin-CDK complexes using phosphorylation? (a) Cdc25 (b) Cdc6 (c) Weel (d) Helicase 9.) What...
Cancer biology 23. The levels of these proteins fluctuate dramatically as cells progress through the cell cycle. These fluctuations are tightly coordinated with the schedule of advances through the various cell cycle phases. For a particular subtype, extracellular signals, notably those conveyed by growth factors, strongly influence their levels. These proteins are: cdc25-like phosphatases b. Cdk kinases c. Protectins d. Cyclins 24. Which of the following best describes the biochemistry that correlates to one of the cell cycle functions of...