Question

Which of the following statements accurately describe receptor tyrosine kinases (RTKs)? There is more than one correct answer. Select all the true statements.

A) A ligand binds to the extracellular domain.

B) RTKs are usually (but not always) monomeric in the absence of ligand.

C) Ligand binding is required for autophosphorylation (cross-phosphorylation).

D) The intracellular domain has phosphatase domains.

E) The alpha subunit contains seven alpha helices that span the membrane.

F) The structure includes a transmembrane helix.

Answer 1

Correct statements:

A) A lignd binds to extracellular domain

B) RTKs are usually (but not always) monomeric in the absence of ligand.

C) Ligand binding is required for autophosphorylation.

F) The structure includes a transmembrane helix.