Can you please help me with this problem:
1 birth requires 2 gametes.
50,000 births will require 2 × 50,000 = 1,00,000 gametes = 10^5
10^6 gametes = 20 mutations
10^5 gametes = 20/10^6 × 10^5 = 2 mutations
So, 10^5 gametes or 50,000 births will show 2 mutations.
Hence, out of 50,000 births, 2 will have retinoblastoma.
Please ratr high.
Can you please help me with this problem: 2. If the new mutation rate for Retinoblastoma...
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Miniature wings (min) is an X-linked recessive mutation in flies. If a min-winged female is crossed to a wild-type male, what proportion of the Fį will have min wings? A. 0% B. 25% C. 50% D. 100% Vladimir is a carrier for diastrophic dysplasia (Dd), an autosomal recessive disorder and has achondroplasia, which is an autosomal dominant trait (Aa). Sophie is also a carrier for diastrophic dysplasia and also...
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2. A woman has two dominant traits, each caused by a mutation in a different gene: cataract (an eye abnormality), which she inherited from her father, and polydactyly (an extra finger), which she inherited from her mother. Her husband has neither trait. a) Sketch a pedigree for this family. (3 pts) b) Write the genotypes of the woman and her husband. (2 pts) c) If the genes for these two traits are...
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5. In an organism where 2N = 20, how many unique gametes could be produced due to independent assortment alone (not considering crossing over)? Briefly explain. 6. One of the autosomal loci controlling eye color in fruit flies has two alleles, one for brown eyes and the other for red eyes. Fruit flies from a true-breeding line with brown eyes were crossed with flies form a true-breeding line with red eyes. The Fı...
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TS =Tumor Suppressor genes
O = Oncogenes
5A. (12pts) Cancer is a genetic disease. Some of the causative mutations are Tumor Suppressor genes, and others convert proto-oncogenes into Oncogenes. In the list of properties below, mark an X in the column for TS, O, or both. TS O both Causes of inherited elevated cancer risk. Leads to uncontrolled cell growth. Typically, spontaneous, gain-of-function mutations. Can cause increased DNA damage. Dominant in...
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An example of linked genes in Drosophila The genes for wing shape and body color are linked (they are on the same chromosome) Drosophila and linked genes In the example shown left, wild type alleles are dominant and are given an upper case symbol of the mutant phenotype (Cu or Eb). This notation used for Drosophila departs from the convention of using the dominant gene to provide the symbol. This is necessary...
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Part 2 (1 point) See Hint Mutation of the muscle-specific intermediate filament desmin leads to the rare disease desmin-related myopathy. This disorder starts with weakness of the lower limbs when patients are in their 20s or 30s. As symptoms worsen, weakness in respiratory and cardiac muscles occurs, which can lead to serious problems including sudden cardiac arrest. Which of the following mutations would disrupt desmin intermediate filament structure or function and could explain the symptoms of...
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Scaly knuckles is a rare autosomal dominant condition in humans that is only 80% penetrant. What is the probability that a child born to a father known NOT to carry the mutation and a mother with scaly knuckles will have the condition A. 0.8 B. 0.5 C. 0.4 D. 0.2 What is the probability that a child of H and I will be affected? DO A. 1/2 B. 1/4...
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3. A dominant wild-type allele D produces full enzyme function, but a recessive alleled, produces no functional enzymatic action, and a recessive allele da produces reduced enzyme function. Western blot analysis of the proteins produced by organisms with different genotypes for this gene gives the results shown. Note, proteins separate out in a gel by size similar to DNA fragments with smaller polypeptides traveling farther. Genotype DD Dd, Dd, dod, dd₂ d₂d₂...
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« EQ Question 17 (2 points) An ideal solenoid is 250 cm long with a cross-sectional area of 1.00 x 10-4 m2 and has 800 turns of wire. (uo = 411 x 10-7 T.m/A). What is the self-inductance of the solenoid? (2 pts)
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3. Sketch a cell where N=4 (3 pts), and answer the following: a. Can this cell do mitosis? If so, describe the outcome in terms of the number of cells, their ploidy and their chromosome number. If not, explain why. b. Can this cell do meiosis? If so, describe the outcome in terms of the number of cells, their ploidy and their chromosome number. If not, explain why. 4. Assume you have...