When neurotransmitters bind to metabotropic receptors, they bind to the _________ of the receptor, causing the receptor to change shape, which is the first step in an intracellular signaling cascade. One essential neurotransmitter, acetylcholine, can generally exert excitatory effects when binding to its ionotropic receptors but can have either excitatory or inhibitory effects when binding to _____________ receptors. When neurotransmitters like acetylcholine bind to _________ receptors they let ions (e.g. Na+, Cl-) into the neuron directly through that channel they are binding to.
Group of answer choices
External component; muscarinic; ionotropic
Internal component; muscarinic; ionotropic
Internal component; nicotinic; metabotropic
External component; nicotinic; metabotropic
Option A is correct. G protein-coupled receptors are inherently metabotropic receptors. Neurotransmitters bind to receptors to the external component and activate cascade of events intracellularly. It involve asa range of secondary messangers.
Another type of receptors are ionotropic. It opens a chhanel that allows ions(Na+, K+ or Cl-) to flow.
When neurotransmitters bind to metabotropic receptors, they bind to the _________ of the receptor, causing the...
20) After a neurotransmitter is released, it must _____________ to the postsynaptic receptor to induce an excitatory postsynaptic potential or an inhibitory postsynaptic potential. All of the answers provided are correct Bind None of the answers provided are correct Be degraded by enzymes before binding 22) Which of the following is a method for terminating an action potential? Postsynaptic binding All of the answers provided are correct Reuptake Enzymatic degredation 23) Drugs of abuse exert their effects in the brain...
"When inhibitory neurotransmitters bind to their receptors in the post-synaptic cell," positively charged ions flow through the ligand-gated ion channel increasing the chance that an action potential can be fired in the post-synaptic cell negatively charged ions flow through the ligand-gated ion channel decreasing the chance that an action potential can be fired in the post-synaptic cell positively charged ions flow through the stress-gated ion channel increasing the chance that an action potential can be fired in the post-synaptic cell...
11. Acetylcholine is both an excitatory and inhibitory ligand depending on the location of its receptor. What does Acetylcholine do that makes it "excitatory"? a. It causes a cell membrane to depolarize and produce Excitatory Post Synaptic Potentials b. It opens K+ ion channels when it binds to its receptors c. It causes a cell membrane to hyperpolarize 12. The bonding of Acetylcholine to its muscarinic receptors on smooth muscle causes gated K+ channels to close. This action is described...
31. Which statement correctly describes a difference be n ionotropic and metabotropic receptors! alonocropic receptors a tough secondary messenger b. Only oncopic receptors are membrane protein clonotropic receptors are directly linked and metabotropic receptors are indirect linked to lon channels d. Neurotransmitters are only involved with incroc receptors. e longropic receptors act owly, while metabotropic act quiddy w ould explan th 32. In an experiment, the membrane potential of a neuron is hyperpolated -120 mW. When an inhibitory neurotransmitter is...
If you only need to have a small amount of a ligand available to have it bind to a receptor and activate it, we would say that ligand has a _________ for that receptor. For example, when glucocorticoid levels are low, they bind to mineralocorticoid receptors (MR) first because they have a ___________ for glucocorticoids, whereas it takes a higher concentration of glucocorticoids to have them bind to glucocorticoid receptors (GR). GRs are g-protein coupled receptors, and we know that...
Complete each sentence to assess your knowledge of neurotransmitter storage and release at a typical neuronal synapse. Thank you!!! Complete each sentence to assess your knowledge of neurotransmitter storage and release at a typical neuronal synapse, SNARE As action potentials propagate along a myelinated fiber, they jump from one node of Ranvier to the next and for this reason such propagation is called reuptake presynaptic Eventually, the action potential reaches the terminal of the neuron postsynaptic Depolarization in the terminat...
Question 1 (1 point) Vasoconstriction occurs when epinephrine (adrenaline) binds to the a-adrenergic receptor on vascular smooth muscle cells. One way to treat high blood pressure is to administer competitive inhibitors that bind to this receptor. The Kd for binding of epinephrine to this receptor is ~UM. Based on the measured affinity (Kd) of the following drugs for the a-adrenergic receptor, which might be good candidates for high blood pressure medication? Drug A: Kd = 0.6 M; Drug B: Kd...
Olfaction occurs when volatile compounds bind to specific odorant receptors. In mammals, each olfactory receptor neuron in the olfactory nasal epithelium expresses a single type of odorant receptor. These odorant receptors constitute a large multigene family (>1000 members) of related proteins. Binding of odorant induces a signaling cascade that is mediated via a G protein, Gaolf. Recent studies suggest that there are a small number of olfactory sensory neurons in the nasal epithelium that express members of the trace-amine associated...
Need help on these questions ? 1.) Steroid hormones trigger transcription of target genes by... a. activating the release of Ca+2 ions that bind to and activate transcription factors. b. activating a kinase cascade that results in the activation of a transcription factor for a set of genes. c. binding directly to DNA and stimulating transcription. d. binding to nuclear receptors that act as transcription factors for specific genes. 2.) Which type of cell-surface receptor(s), when...
8 A reflex are a) is the simplest neural circuit b) requires a receptor, sensory neuron, integration center, motor neuron e) san cause a motor response before a person is consciously aware of it All the above (a, b and c) are corect 9. The correct distribution of spinal nerves is I coccygeal a) 4 cervical, 16 thoracie, 3 lumbar, 8 sacral and b) 12 cervical, 12 thoracic, 3 lumbar, 8 sacral and I coccyseal c) 8 cervical, 12 thoracic,...