Question

Which statement is correct for biological DNA replication?

Select one:

a. DNA polymerases always require a primer.

b. It needs the single strand binding proteins.

c. DNA replication starts at the Ori sequence.

d. DnaA is a protein which steadily accumulates to trigger DNA replication in E.coli.

e. All of these

Answer 1

For biological DNA replication e. All of these are correct.

1) To initiate DNA replication DNA polymerases require a primer with a free 3'-hydroxyl group already base paired to the template.On the other hand RNA polymerase can initiate RNA synthesis without a primer.

2) During DNA replication Single Strand Binding Proteins (SSB) molecules bind to the newly separated individual DNA strands.

3) DNA replication starts at a particular sequence in a genome called Origin of replication.(Ori sequence)

4) DnaA is a protein which steadily accumulates to trigger DNA replication in E.coli.Along with DnaA , DnaB and DnaC also help in DNA replication in E.coli.

Hence all given statements are correct regarding biological DNA replication.