Which of the following statements about eukaryotic DNA replication is false? A) DNA polymerase can add...
Which of the following statements about eukaryotic DNA replication is false?
A) DNA polymerase can add new nucleotides to either free 3'- or 5'-end
B) RNA primers must be removed and rejected by the deoxynucleotides
C) RNA primers must be laid down during DNA replication for synthesis of new DNA that starts at the 3'-OH of the primer ends
D) Elongation of the DNA strand during replication requires primers with free 3'OH end
E) The very end of the chromosome always loses some nucleotides each time DNA replication.
Homework Answers
A) The DNA polymerase can add new nucleotides to either free 3'- or 5'-end.
DNA polymerase adds a new nucleotide to elongate the strand only at free 3'end. It starts with free 3-OH end of primer(which is added to the DNA strand so that initiation can take place) where new deoxynucleotide is added one after another complementarily to the strand. That's why DNA replication takes place only in 5' to 3' direction.
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