Homework Answers
Ans: The correct option is B.
Gluconeogenesis occurs in liver and kidney. Pyruvate carboxylase enzyme converts pyruvate to oxaloacetate so that it can take part in gluconeogenesis process.
In absemce of Pyruvate carboxylase. gluconeogenesis process is affected and pyruvate gets converted to lactic acid that results in lactic acid build up.
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Which of the following processes will be affected by a deficiency in pyruvate carboxylase? gluconeogenesis in...
1. Which enzyme is NOT part of the GNG process? a .Pyruvate kinase b. Pyruvate carboxylase...
1. Which enzyme is NOT part of the GNG process? a .Pyruvate kinase b. Pyruvate carboxylase c. Phosphoenolpyruvate carboxykinsase d. Glucose-6-phosphatase 2. Which molecule can NOT be derived from pyruvate in human? a. Oxaloacetate b. Acetyl CoA c. Lactate d. Ethanol 3. Which one of the following statements regarding the ruminant gluconeogenesis process is correct? a. It leads to net gain of ATP. b. It begins with propionate. c. It begins with lactate. d. It begins with pyruvate.
1. 2. 3. 4. 5. A patient presents with a deficiency of thiamine. If this patient's...
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A patient presents with a deficiency of thiamine. If this patient's liver cells are compared with normal cells, which of the following products would be decreased in the thiamine-deficient cell (when compared to the normal cells) if the cells are only given glucose as a fuel? O Alanine O co2 Lactate O NADP+ e Pyruvate A patient is newly diagnosed with a deficiency in fructokinase. Which of the following will not be a metabolic consequence...
3 20 The conversion pyruvate to either ethanol or lactate occurs A. when there is an abundance of pyruvate but a deficiency of onygen B. when there is an abundance of BOTH pyruvate and oxygen C....
3 20 The conversion pyruvate to either ethanol or lactate occurs A. when there is an abundance of pyruvate but a deficiency of onygen B. when there is an abundance of BOTH pyruvate and oxygen C. when there is a deficiency of BOTH pyruvate and oxygen D. for the regeneration of NADH so that hydrolysis of ATP can continue to fuel the glycolysis pathway Explain how gluconeogenesis differs from gtycolysis 21 Gluconeogenesis is simply the reverse of all 10 steps...
14. Which of the following enzymes is involved in both glass and gluconeogenesis Pyruvate carboxylase, b....
14. Which of the following enzymes is involved in both glass and gluconeogenesis Pyruvate carboxylase, b. Phosphofructokinase 1 Triose phosphate Isomerse Pyruvate kinase Heroine 15- Arsenal is an ion that can replace inorganic phosphate (Pi) is the reaction catalyzed by Glyceraldehyde 3-phosphate dehydrogenase, causing the direct conversion of Glyceraldehyde-3 phosphate into - phosphoglycente. NADH is will produced. Which of the following glycolytic metabolites will not be detectable in a cell that is exposed to reale? Glucose 6-phosphate b. Fructose 6-phosphate...
Match the description to the approptiate cell type gluconeogenesis pathway is unfavorable glycolysis pathway is favorable...
Match the description to the approptiate cell type gluconeogenesis pathway is unfavorable glycolysis pathway is favorable expresses phosphofructokinase y glycerol stimulates the rate of 1. muscle 2. liver cell 3. both 4. neither glucose formation reciprocally regulates glycolysis and gluconeogenesis regulates the rate of expresses pyruvate carboxylase y cannot regulate the rate of expresses fructose 1.6 bisphosphatase Match the description with the process to which it applies transports glucose into mitochondria AMP regulates rate stimulated by high cellular glucose concentration...
4. Which of the following enzymes catalyzed reactions in glycolysis require(s) ATP as a substrate? A)...
4. Which of the following enzymes catalyzed reactions in glycolysis require(s) ATP as a substrate? A) Phosphoglycerate mutase E) Pyruvate kinase B) Aldolase F) Phosphofructokinase-1 C) Phosphoglycerate kinase G) Hexokinase D) Glyceraldehyde-3-phosphate dehydrogenase 5. Blood Lactate Levels during Vigorous Exercise The following graph shows the concentrations of lactate in blood plasma before, during, and after a 400 m sprint. Use your knowledge from chapter 14 to explain the causes of the rapid rise in lactate concentration? --Before-- - After Blood...
A drug company attempted to bypass the need for insulin in diabetics by testing a drug...
A drug company attempted to bypass the need for insulin in diabetics by testing a drug that inhibits adenylate cyclase. Discuss the following questions in regard to glycolysis/gluconeogenesis. 1. What would a decrease in adenylate cyclase do to glucose metabolism in the liver (explain in detail pathway/enzyme regulation/overall effect)? How would this possibly affect blood sugar? a. b. Will this drug be a success? What is the potential overall effect of this drug in diabetic humans (would energy usage or...
During clinical rounds, you encounter patients who exhibit defects that affect gluconeogenesis. Predict the effect that...
During clinical rounds, you encounter patients who exhibit defects that affect gluconeogenesis. Predict the effect that each of the following conditions/defects would have on gluconeogenesis. Explain your prediction and indicate what life style change the patient might make to alleviate the symptoms. a) Patient 1 exhibits a deficiency of the liver lactate dehydrogenase activity. b) Patient 2 exhibits defective liver glucagon receptors which cannot bind glucagon. c) Patient 3 exhibits a constitutively phosphorylated liver phosphofructokinase-2 to lock the bifunctional enzyme...
1. A patient presents in your surgery with an inability to maintain blood sugar levels in...
1. A patient presents in your surgery with an inability to maintain blood sugar levels in long periods (20 hours) between meals. Tests show that glucose is converted to lactate normally in liver in the well-fed state, and that pyruvate carboxylase and phosphoenolpyruvate carboxykinase have normal activities in liver in periods between meals. Your colleague reminds you that glucagon stimulates glycogen degradation, so you administer glucagon to the patient (who was well fed prior to the test) and find that...
Which of the following metabolic changes will occur in a typical human after a meal balanced...
Which of the following metabolic changes will occur in a typical human after a meal balanced in carbohydrates, protein, and fat is consumed? (Select ALL that apply!) Liver glycogen synthesis increases Muscle glycogenolysis (glycogen breakdown) increases Liver gluconeogenesis decreases Insulin levels in the blood decrease Ketone body production in the liver is increased ..... Which of the following metabolic changes will occur in a typical human during 12 hours of fasting? (Select ALL that apply.) Liver glycogen synthesis decreases Liver...
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A patient presents with a deficiency of thiamine. If this patient's liver cells are compared with normal cells, which of the following products would be decreased in the thiamine-deficient cell (when compared to the normal cells) if the cells are only given glucose as a fuel? O Alanine O co2 Lactate O NADP+ e Pyruvate A patient is newly diagnosed with a deficiency in fructokinase. Which of the following will not be a metabolic consequence...
3 20 The conversion pyruvate to either ethanol or lactate occurs A. when there is an abundance of pyruvate but a deficiency of onygen B. when there is an abundance of BOTH pyruvate and oxygen C. when there is a deficiency of BOTH pyruvate and oxygen D. for the regeneration of NADH so that hydrolysis of ATP can continue to fuel the glycolysis pathway Explain how gluconeogenesis differs from gtycolysis 21 Gluconeogenesis is simply the reverse of all 10 steps...
14. Which of the following enzymes is involved in both glass and gluconeogenesis Pyruvate carboxylase, b. Phosphofructokinase 1 Triose phosphate Isomerse Pyruvate kinase Heroine 15- Arsenal is an ion that can replace inorganic phosphate (Pi) is the reaction catalyzed by Glyceraldehyde 3-phosphate dehydrogenase, causing the direct conversion of Glyceraldehyde-3 phosphate into - phosphoglycente. NADH is will produced. Which of the following glycolytic metabolites will not be detectable in a cell that is exposed to reale? Glucose 6-phosphate b. Fructose 6-phosphate...
Match the description to the approptiate cell type gluconeogenesis pathway is unfavorable glycolysis pathway is favorable expresses phosphofructokinase y glycerol stimulates the rate of 1. muscle 2. liver cell 3. both 4. neither glucose formation reciprocally regulates glycolysis and gluconeogenesis regulates the rate of expresses pyruvate carboxylase y cannot regulate the rate of expresses fructose 1.6 bisphosphatase Match the description with the process to which it applies transports glucose into mitochondria AMP regulates rate stimulated by high cellular glucose concentration...
4. Which of the following enzymes catalyzed reactions in glycolysis require(s) ATP as a substrate? A) Phosphoglycerate mutase E) Pyruvate kinase B) Aldolase F) Phosphofructokinase-1 C) Phosphoglycerate kinase G) Hexokinase D) Glyceraldehyde-3-phosphate dehydrogenase 5. Blood Lactate Levels during Vigorous Exercise The following graph shows the concentrations of lactate in blood plasma before, during, and after a 400 m sprint. Use your knowledge from chapter 14 to explain the causes of the rapid rise in lactate concentration? --Before-- - After Blood...
A drug company attempted to bypass the need for insulin in diabetics by testing a drug that inhibits adenylate cyclase. Discuss the following questions in regard to glycolysis/gluconeogenesis. 1. What would a decrease in adenylate cyclase do to glucose metabolism in the liver (explain in detail pathway/enzyme regulation/overall effect)? How would this possibly affect blood sugar? a. b. Will this drug be a success? What is the potential overall effect of this drug in diabetic humans (would energy usage or...
1. A patient presents in your surgery with an inability to maintain blood sugar levels in long periods (20 hours) between meals. Tests show that glucose is converted to lactate normally in liver in the well-fed state, and that pyruvate carboxylase and phosphoenolpyruvate carboxykinase have normal activities in liver in periods between meals. Your colleague reminds you that glucagon stimulates glycogen degradation, so you administer glucagon to the patient (who was well fed prior to the test) and find that...
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