Homework Answers
ATP - Normally cellular ATP (adenosine triphosphate) concentration is maintained in a typical cell in the range of 1 to 10 mmol/L, with a normal ratio of ATP/ADP of approximately 1000. In adults the total quantity of ATP is approximately 0.10 mol/L. Hence this is not the correct answer.
Fructose 6 phosphate - Fructose 6-phosphate lies within the glycolysis metabolic pathway and is produced by isomerisation of glucose 6-phosphate. This is not an adenine nucleotide. Hence this is not the correct answer.
Phosphoenolpyruvate - Phosphoenolpyruvate (2-phosphoenolpyruvate, PEP) exists as an anion and an important intermediate i. It is the ester derived from of the enol of pyruvate and phosphate. It exists as an anion. This is not an adenine nucleotide. Hence this is not the correct answer.
NADH - NADH (nicotinamide adenine dinucleotide (NAD) + hydrogen (H)) acts as a shuttle for electrons during cellular respiration. Hence this is also not the correct answer.
AMP - AMP is a physiological regulator with affinities of the two exchangeable sites. AMP is normally present at much lower cellular concentrations in a typical cell. Hence AMP is the correct answer.
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Which adenine nucleotide is present in the lowest concentration in the typical cell? ATP fructose 6-phosphate...
Question 4 Q . OH ATP OH POH ОН Fructose 6-phosphate Fructose 1.6-bisphosphate Figure 1. Reaction...
Question 4 Q . OH ATP OH POH ОН Fructose 6-phosphate Fructose 1.6-bisphosphate Figure 1. Reaction catalyzed by phosphofructokinase (PFK) during glycolysis Phosphofructokinase (PFK) is an enzyme that catalyzes the conversion of fructose 6- phosphate to fructose 1,6-bisphosphate during glycolysis, as represented in Figure 1. PFK can be allosterically inhibited by ATP at high concentrations. Which of the following is the benefit of regulating glycolysis by the concentration of ATP? Glycolysis proceeds when the intracellular concentration of ATP is low,...
GLYCOLYSIS Glucose-8 phosphate + Glucose 2 Fructose-6-phosphate 3 Fructose-1,6-biphosphate Dihydroxy-acetone-phosphate 5 Glyceraldehyde-3-phosphate VT6 2 (1,3-biphosphoglycerate) 7...
GLYCOLYSIS Glucose-8 phosphate + Glucose 2 Fructose-6-phosphate 3 Fructose-1,6-biphosphate Dihydroxy-acetone-phosphate 5 Glyceraldehyde-3-phosphate VT6 2 (1,3-biphosphoglycerate) 7 3-phosphoglycerate 2-phosphoglycerate 9 phosphoenolpyruvate 10 Lactate Pyruvate Which two reactions of glycolysis requires an investment of ATP energy, and which enzyme catalyzes each reaction? Reaction Number Enzyme Reaction Number Enzyme Which two reactions of glycolysis generate energy in the form of ATP, and which enzyme catalyzes each reaction? Reaction Number Enzyme Reaction Number Enzyme Which glycolytic reaction generates energy in the form of NADH,...
Why are these reactions for gluconeogenesis exergonic? I get that Glucose 6-phosphate -> glucose and fructose...
Why are these reactions for gluconeogenesis
exergonic?
I get that Glucose 6-phosphate -> glucose and fructose
1,6-biphosphate -> fructose 6 phosphate release Pi, but doesn't
the formation of formation of oxaloacetate and phosphoenolpyruvate
require energy ( ATP and GTP)
ruvate. CH,OH CHOPO; HO он glucose 6- phosphatase HO OH OH 94 Он glucose 6-phosphate glucose glycolysao OPOH COCHZOPO HO O HO OH fructose 1,6- bisphosphatase ,POH COCH,OH HO он OH fructose 6-phosphate OH fructose 1,6-bisphosphate HCO; + ATP ADP +...
match the following 1. Fructose 1,6-bisphosphate is converted to Fructose 6- phosphate through this enzyme _____...
match the following 1. Fructose 1,6-bisphosphate is converted to Fructose 6- phosphate through this enzyme _____ 2. Synthesis of glucose from noncarbohydrate precursors _____ 3. Stage in which two molecules of ATP are consumed _____ 4. This is formed from pyruvate in yeast and several other microorganisms through fermentation _____ 5. The isomerization of glucose 6-phosphate to fructose 6-phosphate is a coversion of an aldose into a …._____ 6. Pyruvate is converted by pyruvate carboxylase into this intermediate _____ 7....
In a cell, the concentration of glucose-6-phosphate is 83 μM and of fructose-6-phosphate is 14 μM....
In a cell, the concentration of glucose-6-phosphate is 83 μM and of fructose-6-phosphate is 14 μM. The ΔG°' = 410 cal/mol for the conversion of glucose-6-phosphate to fructose-6-phosphate. Assume the gas constant “R” is 1.987 and T is 298K. Based upon this information, the ΔG’ for this reaction (in cal/mol) is?
The concentration of fructose 6-phosphate (F6P) and fructose 1, 6-biphosphate (F16BP), ATP, and ADP in muscle...
The concentration of fructose 6-phosphate (F6P) and fructose 1, 6-biphosphate (F16BP), ATP, and ADP in muscle tissue were measured as 0.089, 0.012, 12.0, and 1.2 mM. For the reaction F6P(aq) + ATP(aq) rightarrow F16BP(aq) + ADP(aq) at 37 degree C, the standard Gibbs energy (at pFl=7) is -18.3 kJ/mol. Calculate the reaction Gibbs energy (kJ/mol) for the reaction in the muscle tissue environment. -71.2 -29.4 -7.3 +4.5 +11.2.
a. Which step in glycolysis is the major control point? Step 10, the addition of phosphate...
a. Which step in glycolysis is the major control point? Step 10, the addition of phosphate to phosphoenolpyruvate. Step 3, the addition of phosphate to fructose 6-phosphate. Step 1, the addition of phosphate to glucose. b. What compounds act as positive effectors of the enzyme that catalyzes this reaction? Citrate МАТР O Pyruvate ADP AMP c. What compounds are negative effectors? O AMP Citrate ADP ATP Glucose
Why would excess Fructose-6-Phosphate be a signal for the cell to increase the activity of pyruvate...
Why would excess Fructose-6-Phosphate be a signal for the cell to increase the activity of pyruvate kinase, the enzyme that converts phosphoenolpyruvate to pyruvate?
the enzyme hexokinase can catalyze the following reaction: fructose + ATP -> fructose 6 phosphate +...
the enzyme hexokinase can catalyze the following
reaction:
fructose + ATP -> fructose 6 phosphate + adp
if the deltaG of hydrolysis of fructose 6 phosphate to
fructose + Pi is -13.8 kj/mol and hydrolysis of atp to adp + pi is
-30kj/mol, calculate Keq for the reaction above (R = 8.31 j mol-1
K-1, T = 298 k
3a. The enzyme hexokinase can catalyze the following reaction: Fructose + ATP → Fructose-6-phosphate + ADP If the ΔGo of hydrolysis...
A highly regulated reaction in glycolysis involves the addition of a second phosphate to fructose-6-phosphate, which...
A highly regulated reaction in glycolysis involves the addition
of a second phosphate to fructose-6-phosphate, which could be be
written as:
Fructose-6-phostphate + Pi à Fructose-1,6-bisphosphate + H2O
The ∆Go’ for this reaction is +16.8 kJ/mol
In a muscle cell at 37 oC, assume the concentration of
Fructose-6phosphate is 0.014 mM and the concentration of phosphate
is 1 mM.
a. What would be the equilibrium concentration of
fructose-1,6bisphosphate under these conditions?
b. What is Keq for this reaction?
Show...
Question 4 Q . OH ATP OH POH ОН Fructose 6-phosphate Fructose 1.6-bisphosphate Figure 1. Reaction catalyzed by phosphofructokinase (PFK) during glycolysis Phosphofructokinase (PFK) is an enzyme that catalyzes the conversion of fructose 6- phosphate to fructose 1,6-bisphosphate during glycolysis, as represented in Figure 1. PFK can be allosterically inhibited by ATP at high concentrations. Which of the following is the benefit of regulating glycolysis by the concentration of ATP? Glycolysis proceeds when the intracellular concentration of ATP is low,...
GLYCOLYSIS Glucose-8 phosphate + Glucose 2 Fructose-6-phosphate 3 Fructose-1,6-biphosphate Dihydroxy-acetone-phosphate 5 Glyceraldehyde-3-phosphate VT6 2 (1,3-biphosphoglycerate) 7 3-phosphoglycerate 2-phosphoglycerate 9 phosphoenolpyruvate 10 Lactate Pyruvate Which two reactions of glycolysis requires an investment of ATP energy, and which enzyme catalyzes each reaction? Reaction Number Enzyme Reaction Number Enzyme Which two reactions of glycolysis generate energy in the form of ATP, and which enzyme catalyzes each reaction? Reaction Number Enzyme Reaction Number Enzyme Which glycolytic reaction generates energy in the form of NADH,...
Why are these reactions for gluconeogenesis
exergonic?
I get that Glucose 6-phosphate -> glucose and fructose
1,6-biphosphate -> fructose 6 phosphate release Pi, but doesn't
the formation of formation of oxaloacetate and phosphoenolpyruvate
require energy ( ATP and GTP)
ruvate. CH,OH CHOPO; HO он glucose 6- phosphatase HO OH OH 94 Он glucose 6-phosphate glucose glycolysao OPOH COCHZOPO HO O HO OH fructose 1,6- bisphosphatase ,POH COCH,OH HO он OH fructose 6-phosphate OH fructose 1,6-bisphosphate HCO; + ATP ADP +...
The concentration of fructose 6-phosphate (F6P) and fructose 1, 6-biphosphate (F16BP), ATP, and ADP in muscle tissue were measured as 0.089, 0.012, 12.0, and 1.2 mM. For the reaction F6P(aq) + ATP(aq) rightarrow F16BP(aq) + ADP(aq) at 37 degree C, the standard Gibbs energy (at pFl=7) is -18.3 kJ/mol. Calculate the reaction Gibbs energy (kJ/mol) for the reaction in the muscle tissue environment. -71.2 -29.4 -7.3 +4.5 +11.2.
a. Which step in glycolysis is the major control point? Step 10, the addition of phosphate to phosphoenolpyruvate. Step 3, the addition of phosphate to fructose 6-phosphate. Step 1, the addition of phosphate to glucose. b. What compounds act as positive effectors of the enzyme that catalyzes this reaction? Citrate МАТР O Pyruvate ADP AMP c. What compounds are negative effectors? O AMP Citrate ADP ATP Glucose
the enzyme hexokinase can catalyze the following
reaction:
fructose + ATP -> fructose 6 phosphate + adp
if the deltaG of hydrolysis of fructose 6 phosphate to
fructose + Pi is -13.8 kj/mol and hydrolysis of atp to adp + pi is
-30kj/mol, calculate Keq for the reaction above (R = 8.31 j mol-1
K-1, T = 298 k
3a. The enzyme hexokinase can catalyze the following reaction: Fructose + ATP → Fructose-6-phosphate + ADP If the ΔGo of hydrolysis...
A highly regulated reaction in glycolysis involves the addition
of a second phosphate to fructose-6-phosphate, which could be be
written as:
Fructose-6-phostphate + Pi à Fructose-1,6-bisphosphate + H2O
The ∆Go’ for this reaction is +16.8 kJ/mol
In a muscle cell at 37 oC, assume the concentration of
Fructose-6phosphate is 0.014 mM and the concentration of phosphate
is 1 mM.
a. What would be the equilibrium concentration of
fructose-1,6bisphosphate under these conditions?
b. What is Keq for this reaction?
Show...
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