Why would excess Fructose-6-Phosphate be a signal for the cell to increase the activity of pyruvate...
Why would excess Fructose-6-Phosphate be a signal for the cell to increase the activity of pyruvate kinase, the enzyme that converts phosphoenolpyruvate to pyruvate?
Homework Answers
The excess of fructose -6 phosphate is converted into fructose 1-6 bisphosphate. The fructose 1-6 bisphosphate acts as an allosteric activator of the pyruvate kinase enzyme. In this way, the fructose 1-6 bisphosphate concentration is increased with increase of fructose 6 phosphate. This fructose-6 phosphate binds with pyruvate kinase enzyme. And enhances the binding of phosphoenol pyruvate to the enzyme. Due to allosteeic activity of fructose -1-6 bisphosphate, the activity of pyruvate kinase enzyme is increases.
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Why would excess Fructose-6-Phosphate be a signal for the cell
to increase the activity of pyruvate...
match the following 1. Fructose 1,6-bisphosphate is converted to Fructose 6- phosphate through this enzyme _____...
match the following 1. Fructose 1,6-bisphosphate is converted to Fructose 6- phosphate through this enzyme _____ 2. Synthesis of glucose from noncarbohydrate precursors _____ 3. Stage in which two molecules of ATP are consumed _____ 4. This is formed from pyruvate in yeast and several other microorganisms through fermentation _____ 5. The isomerization of glucose 6-phosphate to fructose 6-phosphate is a coversion of an aldose into a …._____ 6. Pyruvate is converted by pyruvate carboxylase into this intermediate _____ 7....
During the EMP pathway, why would the cell want the pyruvate kinase be positively regulated by...
During the EMP pathway, why would the cell want the pyruvate kinase be positively regulated by high levels of fructose-6-phosphate?
Why are these reactions for gluconeogenesis exergonic? I get that Glucose 6-phosphate -> glucose and fructose...
Why are these reactions for gluconeogenesis
exergonic?
I get that Glucose 6-phosphate -> glucose and fructose
1,6-biphosphate -> fructose 6 phosphate release Pi, but doesn't
the formation of formation of oxaloacetate and phosphoenolpyruvate
require energy ( ATP and GTP)
ruvate. CH,OH CHOPO; HO он glucose 6- phosphatase HO OH OH 94 Он glucose 6-phosphate glucose glycolysao OPOH COCHZOPO HO O HO OH fructose 1,6- bisphosphatase ,POH COCH,OH HO он OH fructose 6-phosphate OH fructose 1,6-bisphosphate HCO; + ATP ADP +...
1.Predict the effect of a large amount of acetyl-CoA on the activity of pyruvate dehydrogenase and...
1.Predict the effect of a large amount of acetyl-CoA on the activity of pyruvate dehydrogenase and the rate of glycolysis. Note: pyruvate dehydrogenase is the enzyme that catalyzes the formation of acetyl-CoA from pyruvate. a. Pyruvate dehydrogenase activity will decrease while the rate of glycolysis will increase. b. Both pyruvate dehydrogenase activity and the rate of glycolysis will decrease. c. Pyruvate dehydrogenase activity will increase while the rate of glycolysis will decrease. d. The rate of glycolysis will increase, thereby,...
please explain answer Glycolysis. In the third step of glycolysis, the enzyme phosphofructokinase transfers a phosphate...
please explain answer
Glycolysis. In the third step of glycolysis, the enzyme phosphofructokinase transfers a phosphate group from ATP to fructose-6-phophate to generate fructose- 1,6- bisphosphate. In contrast, in step 10, the enzyme pyruvate kinase transfers a phosphate group from phosphoenolpyruvate to ADP to generate ATP. Using what you know about the standard free energy change associated with phosphate bonds, (briefly) explain why we observe this difference.
In order to determine if the patient with the blood results shown here could complete glycolysis,...
In order to determine if the patient with the blood results shown here could complete glycolysis, what substance would you test for in her blood? Blood Metabolic Panel Blood Glucose + Glucose-6-phosphate ++ Fructose-6-phosphate ++ Fructose-1,6,bisphosphate ++ Glyceraldehyde-3-phosphate ++ 1,3-bisphosphoglycerate ++ Phosphoenolpyruvate ++ Pyruvate - ATP - Red Blood Cell Concentration - A. Pyruvate B. Pyruvate kinase (enzyme that preceeds Puruvate)
GLYCOLYSIS Glucose-8 phosphate + Glucose 2 Fructose-6-phosphate 3 Fructose-1,6-biphosphate Dihydroxy-acetone-phosphate 5 Glyceraldehyde-3-phosphate VT6 2 (1,3-biphosphoglycerate) 7...
GLYCOLYSIS Glucose-8 phosphate + Glucose 2 Fructose-6-phosphate 3 Fructose-1,6-biphosphate Dihydroxy-acetone-phosphate 5 Glyceraldehyde-3-phosphate VT6 2 (1,3-biphosphoglycerate) 7 3-phosphoglycerate 2-phosphoglycerate 9 phosphoenolpyruvate 10 Lactate Pyruvate Which two reactions of glycolysis requires an investment of ATP energy, and which enzyme catalyzes each reaction? Reaction Number Enzyme Reaction Number Enzyme Which two reactions of glycolysis generate energy in the form of ATP, and which enzyme catalyzes each reaction? Reaction Number Enzyme Reaction Number Enzyme Which glycolytic reaction generates energy in the form of NADH,...
QUESTION 30 What are the products of the enzyme aldolase in glycolysis? O phosphoglycerate O fructose...
QUESTION 30 What are the products of the enzyme aldolase in glycolysis? O phosphoglycerate O fructose 1-6 diphosphate phosphoenolpyruvate dihydroxyacetone phosphate glyceraldehyde 3-phosphate pyruvate QUESTION 31 What is the substrate for the enzyme aldolase in glycolysis? dihydroxyacetone phosphate glyceraldehyde 3.phosphate pyruvate phosphoenolpyruvate fructose 1-6 diphosphate phosphoglycerate
Which adenine nucleotide is present in the lowest concentration in the typical cell? ATP fructose 6-phosphate...
Which adenine nucleotide is present in the lowest concentration in the typical cell? ATP fructose 6-phosphate AMP phosphoenolpyruvate O NADH
Pyruvate kinase catalyzes the last reaction in the glycolytic pathway: phosphoenolpyruvate (PEP) + ADP --> pyruvate...
Pyruvate kinase catalyzes the last reaction in the glycolytic
pathway:
phosphoenolpyruvate (PEP) + ADP --> pyruvate + ATP
There are four different mammalian forms of pyruvate kinase. All
catalyze the same reaction, but they differ in their response to
the glycolytic metabolite fructose-1,6-bisphosphate (F16BP).
The activity of two forms of pyruvate kinase was measured at
various concentrations of PEP, as shown below. Activity was
measured in the presence (blue circles) and absence (red circles)
of F16BP.
Pyruvate Kinase Form 1...
Why are these reactions for gluconeogenesis
exergonic?
I get that Glucose 6-phosphate -> glucose and fructose
1,6-biphosphate -> fructose 6 phosphate release Pi, but doesn't
the formation of formation of oxaloacetate and phosphoenolpyruvate
require energy ( ATP and GTP)
ruvate. CH,OH CHOPO; HO он glucose 6- phosphatase HO OH OH 94 Он glucose 6-phosphate glucose glycolysao OPOH COCHZOPO HO O HO OH fructose 1,6- bisphosphatase ,POH COCH,OH HO он OH fructose 6-phosphate OH fructose 1,6-bisphosphate HCO; + ATP ADP +...
please explain answer
Glycolysis. In the third step of glycolysis, the enzyme phosphofructokinase transfers a phosphate group from ATP to fructose-6-phophate to generate fructose- 1,6- bisphosphate. In contrast, in step 10, the enzyme pyruvate kinase transfers a phosphate group from phosphoenolpyruvate to ADP to generate ATP. Using what you know about the standard free energy change associated with phosphate bonds, (briefly) explain why we observe this difference.
GLYCOLYSIS Glucose-8 phosphate + Glucose 2 Fructose-6-phosphate 3 Fructose-1,6-biphosphate Dihydroxy-acetone-phosphate 5 Glyceraldehyde-3-phosphate VT6 2 (1,3-biphosphoglycerate) 7 3-phosphoglycerate 2-phosphoglycerate 9 phosphoenolpyruvate 10 Lactate Pyruvate Which two reactions of glycolysis requires an investment of ATP energy, and which enzyme catalyzes each reaction? Reaction Number Enzyme Reaction Number Enzyme Which two reactions of glycolysis generate energy in the form of ATP, and which enzyme catalyzes each reaction? Reaction Number Enzyme Reaction Number Enzyme Which glycolytic reaction generates energy in the form of NADH,...
QUESTION 30 What are the products of the enzyme aldolase in glycolysis? O phosphoglycerate O fructose 1-6 diphosphate phosphoenolpyruvate dihydroxyacetone phosphate glyceraldehyde 3-phosphate pyruvate QUESTION 31 What is the substrate for the enzyme aldolase in glycolysis? dihydroxyacetone phosphate glyceraldehyde 3.phosphate pyruvate phosphoenolpyruvate fructose 1-6 diphosphate phosphoglycerate
Which adenine nucleotide is present in the lowest concentration in the typical cell? ATP fructose 6-phosphate AMP phosphoenolpyruvate O NADH
Pyruvate kinase catalyzes the last reaction in the glycolytic
pathway:
phosphoenolpyruvate (PEP) + ADP --> pyruvate + ATP
There are four different mammalian forms of pyruvate kinase. All
catalyze the same reaction, but they differ in their response to
the glycolytic metabolite fructose-1,6-bisphosphate (F16BP).
The activity of two forms of pyruvate kinase was measured at
various concentrations of PEP, as shown below. Activity was
measured in the presence (blue circles) and absence (red circles)
of F16BP.
Pyruvate Kinase Form 1...
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