During the EMP pathway, why would the cell want the pyruvate kinase be positively regulated by high levels of fructose-6-phosphate?
During the EMP pathway, why would the cell want the pyruvate kinase be positively regulated by...
Why would excess Fructose-6-Phosphate be a signal for the cell to increase the activity of pyruvate kinase, the enzyme that converts phosphoenolpyruvate to pyruvate?
During gluconeogenesis, why would the cell want to have the function of the fructose-6- bisphosphate phosphatase be negatively regulated by high levels of AMP?
All of the following are precursor metabolites produced during EMP except phosphoenolpyruvate (PEP). glyceraldehyde-3-phosphate. oxaloacetate. pyruvate. Fructose-6-phosphate.
Which pair of opposite enzymes in the glycolysis and gluconeogenesis pathway are not allosterically regulated but rather regulated by compartmentalization? Select one: a. pyruvate kinase/PEP carboxykinase b. phosphofructokinase 1/fructose-1,6-bisphosphatase c. phosphofructokinase 2/fructose-2,6-bisphosphatase d. hexokinase/glucose-6-phosphatase
Explain in detail how PFK-1, hexokinase, glucokinase, pyruvate kinase, glucose-6-phosphatase, fructose-1,6-bisphosphatase-1, pyruvate carboxylase & PEPCK are regulated & compare their regulation in liver vs. skeletal muscle & brain when blood glucose levels are high (i.e. a fed state) & low (i.e. a fasting or starvation state).
PART A OPTIONS FOR BLANKS: 1- inhibits, does not affect, stimulates 2- fructose-1,6-biphosphatase-1, pyruvate kinase, phosphofructokinase-1 3- phosphofructokinase-1, fructose-1,6-biphosphatase-1, phosphoenolpyruvate carboxylate PART B OPTIONS FOR BLANK: Activity Curve A, Neither, Activity Curve B Part 1 (3 points) See Hint High levels of fructose-2,6-BP reciprocally regulate glycolysis and gluconeogenesis. Fructose-2,6-BP flux through the glycolytic pathway by increasing the activity of Flux through the gluconeogenic pathway is inhibited by fructose-2,6- BP, which decreases the activity of Part 2 (1 point) See Hint...
QUESTION 2 (A) The pentose phosphate pathway is comprised of two phases. Why are both phases necessary for the survival of the cell? (2pts) (B) In the non-oxidative phase of the pentose phosphate pathway ribose 5-phosphate is converted to fructose 6-phosphate. Why does this pathway require so many enzymatic steps? What benefit does each step provide? (4 pts) (C) Many cancer drugs are effective because they reduce cell proliferation by reducing the amount of base material needed for cell division...
2) if a single glucose molecule was completely catabolized to 2 pyruvate, then the liver built the 2 pyruvate back to glucose, how much free energt would be lost? 4) at which glycolysis metabolite does glycogen synthesis amd the pentose phosphate pathway branch off from? MIBROS JUJILOR DUE 3/13 at the beginning of class CHOH ресто points) OPOCH HO PHY OH OR equal ts3 > Loc Energy 50 Investmen when Phase n ] ohuoc but at Glucose 1)(6) Fill in...
Metabolic Pathway Engineering Problem Set 5 Engineering a Fermentation System: Fermentation of plant matter to produce ethanol for fuel is one potential method for reducing the use of fossil fuels and thus the CO2 emissions that lead to global warming. Many microorganisms can break down cellulose then ferment the glucose to ethanol. However, many potential cellulose sources, including agricultural residues and switchgrass, also contain substantial amounts of arabinose, which is not as easily fermented. Escherichia coli is capable of fermenting...
Please choose the BEST ANSWER. No cell phones, web or cameras, please. 1. Each of the following enzymes functions in both glycolysis and gluconeogenesis except: A) 3-phosphoglycerate kinase B) aldolase C) enolase D) phosphofructokinase-1 E) phosphohexose isomerase During strenuous exercise, the NADH formed in the glyceraldehyde 3-phosphate dehydrogenase reaction in skeletal muscle must be reoxidized to NAD if glycolysis is to continue. The most important reaction involved in this reoxidation of NADH is: 2. A) dihydroxyacetone phosphate> glycerol 3-phosphate B)...