Question

Nrf2 induces inflammation by the upregulation of cytokines such as IL-2. True False

Answer 1

Nrf2 induces inflammation by the upregulation of the cytokines such as IL-2

False.

since, Nrf2 is known to interfere with the upregulation of the cytokines and represses inflammation.

Free radicals can cause disease of the nervous system. Many times there is a defect in the antioxidant gene that leads to the diseased state. One could surmise that if you eat more anti-oxidant type foods, perhaps you could lessen the symptoms. If you knew the genetics of the disease, you could choose specific foods. This is an example of Nutrgenomics.

True.

since, It is the Nutrigenomics, that deals with the type and nutrients present in food, that influence the gene expressions.

Nrf2 through effects on gene expression, activates:

antioxidant status- the ability to neutralize toxins

detoxification mechanisms- the ability to break down toxins.

efflux pumps- the ability to shuttle toxins out of the cell

Hence, All of the above.

Many studies have shown that taking Vitamin C and vitamin E supplements can help to reduce cardiovascular disease.

True.