A rare mutation on the X chromosome is associated with T- and natural killer-cell lymphoproliferative disorder....
A rare mutation on the X chromosome is associated with T- and natural killer-cell lymphoproliferative disorder. To what extent would the two-hit theory apply to this disease?
Homework Answers
Question
The two hit hypothesis of the lymphoproliferative disorder state that a combination of the T cell non-functioning along with natural killer cells non-functioning lead to the weakened immune system in an individual which further lead to the lymphoproliferative disorder. It means two causes summation lead to the formation of this disorder.
Add Answer to:
A rare mutation on the X chromosome is associated with T- and
natural killer-cell lymphoproliferative disorder....
2. Tay-Sachs disease is a genetic disorder caused by a mutation on chromosome 15 that is believed...
Conditional probability
please follow the comment
2. Tay-Sachs disease is a genetic disorder caused by a mutation on chromosome 15 that is believed to occur in roughly 1 in 320000 babies in the U.S. As part of a cutting-edge genomics company, you've designed a new test for Tay-Sachs that is 99.2% accurate (ie, gives a positive result) in those babies that have the disorder, and 97% accurate (i.e. gives a negative result) in babies that don't have the disorder. Suppose...
You are mapping a rare autosomal recessive disorder and linkage points towards a location on chromosome...
You are mapping a rare autosomal recessive disorder and linkage points towards a location on chromosome 7. To refine the location of the disease gene, you determine the genotype for 11 additional markers that map to an approximately 65 Mb region on the long arm of chromosome 7. Alleles for each of these markers are shown for one family. What type of markers are most likely shown? Why do you know this?
Hemophilia A is a genetic disorder of recessive X chromosome mutation of the Factor VIII gene...
Hemophilia A is a genetic disorder of recessive X chromosome mutation of the Factor VIII gene that causes a blood clotting protein Factor VIII missing or deficient. If a person with XY chromosomes is affected by Hemophilia A and a person with XX chromosomes is an unaffected person, what is the probability that their male offspring might be hemophilic and what is the probability that their female offspring might be carriers of the mutated gene?
Assume no natural selection, equal mutation rates across sexes and different chromosome types (X,Y, autosomes). Would...
Assume no natural selection, equal mutation rates across sexes and different chromosome types (X,Y, autosomes). Would you expect X chromosomes and autosomes to have different levels of per site neutral variations within species? What about between species?
Question 1 ips A genetic disorder that is associated with the X-chromosome will likely appear in...
Question 1 ips A genetic disorder that is associated with the X-chromosome will likely appear in more males than females about equally in males and females in slightly more females than males in twice as many females than males Next → Question 2 1 pts means that genes contribute a predisposition for a disorder that may or may not exceed the threshold to produce the disorder. Expression pattern Concordance rate Vulnerability Heritability Question 3 1 pts What is a concern...
What is a diploid cell? One that has two copies of each chromosome – one from...
What is a diploid cell? One that has two copies of each chromosome – one from mom and one from dad. A cell that carries the mutation for Cystic Fibrosis. Another term for a sperm or egg cell. A cell that carries only one copy of the X chromosome
8. [12 pts total] Huntington disease is a rare degenerative autosomal disorder that determined by a...
8. [12 pts total] Huntington disease is a rare degenerative autosomal disorder that determined by a dominant allele. The disorder is typically manifested after the age of 45. A young man has learned that his father has developed the disease; his mother does not carry the dominant allele for the condition [4 pts] A. What is the probability that the young man will later develop the disease? (4 pts] B. If the young man has a child with a woman...
32. The local news has been discussing a specific rare disorder that killed a child in...
32. The local news has been discussing a specific rare disorder that killed a child in the community this week, describing the earliest symptoms of the disease as including nasal congestion, ear pain, and a cough. The pediatrician's office is receiving numerous calls asking to make appointments to rule out this rare disease. What is the nurse's best action? A) Make copies of recent newspaper and online articles that provide parents with more B) Tell parents their child is experiencing...
ww Dong 7. This family has members who suffer from a rare disorder (abbreviated PMĚ) that...
ww Dong 7. This family has members who suffer from a rare disorder (abbreviated PMĚ) that presents with action myoclonus, and progressive neurological decline. (6 pts) Figure 1. Family pedigree and magnetic resonance imaging. (A) The six-generation family showing segregation of PME and ataxia. (B) Normal brain MRI of proband at 9 years. (C) Brain MRI of younger affected sister at 18 months showing callosal agenesis, a large interhemispheric cyst and simplified gyration frontally. PME a. What is the mode...
Given that TP53 is a recessive gene and is not located on the X chromosome, why would people who inherit just one mutant copy of a recessive tumor-suppressor gene be at higher risk of developing cance...
Given that TP53 is a recessive gene and is not located on the X chromosome, why would people who inherit just one mutant copy of a recessive tumor-suppressor gene be at higher risk of developing cancer than those without the recessive gene? Given that is a recessive gene and is not located on the X chromosome, why would people who inherit just one mutant copy of a recessive tumor-suppressor gene be at higher risk of developing cancer than those without...
Conditional probability
please follow the comment
2. Tay-Sachs disease is a genetic disorder caused by a mutation on chromosome 15 that is believed to occur in roughly 1 in 320000 babies in the U.S. As part of a cutting-edge genomics company, you've designed a new test for Tay-Sachs that is 99.2% accurate (ie, gives a positive result) in those babies that have the disorder, and 97% accurate (i.e. gives a negative result) in babies that don't have the disorder. Suppose...
You are mapping a rare autosomal recessive disorder and linkage points towards a location on chromosome 7. To refine the location of the disease gene, you determine the genotype for 11 additional markers that map to an approximately 65 Mb region on the long arm of chromosome 7. Alleles for each of these markers are shown for one family. What type of markers are most likely shown? Why do you know this?
Question 1 ips A genetic disorder that is associated with the X-chromosome will likely appear in more males than females about equally in males and females in slightly more females than males in twice as many females than males Next → Question 2 1 pts means that genes contribute a predisposition for a disorder that may or may not exceed the threshold to produce the disorder. Expression pattern Concordance rate Vulnerability Heritability Question 3 1 pts What is a concern...
8. [12 pts total] Huntington disease is a rare degenerative autosomal disorder that determined by a dominant allele. The disorder is typically manifested after the age of 45. A young man has learned that his father has developed the disease; his mother does not carry the dominant allele for the condition [4 pts] A. What is the probability that the young man will later develop the disease? (4 pts] B. If the young man has a child with a woman...
32. The local news has been discussing a specific rare disorder that killed a child in the community this week, describing the earliest symptoms of the disease as including nasal congestion, ear pain, and a cough. The pediatrician's office is receiving numerous calls asking to make appointments to rule out this rare disease. What is the nurse's best action? A) Make copies of recent newspaper and online articles that provide parents with more B) Tell parents their child is experiencing...
ww Dong 7. This family has members who suffer from a rare disorder (abbreviated PMĚ) that presents with action myoclonus, and progressive neurological decline. (6 pts) Figure 1. Family pedigree and magnetic resonance imaging. (A) The six-generation family showing segregation of PME and ataxia. (B) Normal brain MRI of proband at 9 years. (C) Brain MRI of younger affected sister at 18 months showing callosal agenesis, a large interhemispheric cyst and simplified gyration frontally. PME a. What is the mode...
Most questions answered within 3 hours.
-
You have a 825.3 mL sample of 2.754 M HA (Ka =
4.49⋅10−4). Calculate the pH...
asked 11 minutes ago -
The blues made its way into many kinds of music. Eric Clapton,
The Beatles, and Elvis...
asked 2 hours ago -
8. A wave in a string has a wave function given by: y (x, t) =...
asked 1 hour ago -
If you’re standing at the bottom of a hill and asked to evaluate
it while being...
asked 3 hours ago -
1. Which region has taken the lead in the world of
e-waste handling?
a) European Union...
asked 3 hours ago -
A 8.15- g bullet from a 9-mm pistol has a velocity of 366.0 m/s.
It strikes...
asked 4 hours ago -
The outstanding bonds of Alpha Extracts have a yield to maturity
of 7.4 percent and a...
asked 4 hours ago -
The Problem: The Case of the Harmonizing Vacations
Your CEO is exploring partnering with a European...
asked 5 hours ago -
A chemical equation is balanced by adding coefficients in front
of some formulas so that the...
asked 5 hours ago -
From the literature (reference your sources): What are the
lattice parameters of calcite and aragonite? Why...
asked 6 hours ago -
Your system is rejecting the question am asking which is
preceded by a case study. It...
asked 6 hours ago -
3. On January 2, 2000, Larry creates a trust with himself as
trustee. Larry as trustee...
asked 6 hours ago